Machine learning is a component of artificial intelligence; it relies on computer algorithms and data analysis to learn patterns that exceeds the capacity of the human mind to comprehend. It uses statistical methods to infer relationships between predictors and outcomes in large datasets, and it has been successfully applied to predict adverse events in health care settings. In the preoperative phase, for risk stratification of patients with surgical conditions, various types of supervised learning have been used with large clinical databases. In our work, the aim was to investigate the potential role of machine learning (ML) versus classical statistical methods (SM) for the preoperative risk assessment in proctological surgery. We used clinical data from a nationwide audit: the database consisted of 1510 patients affected by Goligher's grade III hemorrhoidal disease who underwent elective surgery. We collected anthropometric, clinical, and surgical data and we considered ten predictors to evaluate model-predictive performance. The clinical target was the complication rate evaluated at 30-days follow-up. Logistic regression and three ML techniques were compared. ML models included a Decision Tree, a Support Vector Machine, and a classification Extreme Gradient Boosting (XGB). These methodologies could be used to develop a surgical risk calculator, which is already used and widespread for other diseases, that could help clinicians to estimate the chance of an unfavorable outcome after surgery.

Evoluzione delle tecniche chirurgiche in proctologia: valutazione del rischio preoperatorio con modelli di machine learning

ROMANO, LUCIA
2024

Abstract

Machine learning is a component of artificial intelligence; it relies on computer algorithms and data analysis to learn patterns that exceeds the capacity of the human mind to comprehend. It uses statistical methods to infer relationships between predictors and outcomes in large datasets, and it has been successfully applied to predict adverse events in health care settings. In the preoperative phase, for risk stratification of patients with surgical conditions, various types of supervised learning have been used with large clinical databases. In our work, the aim was to investigate the potential role of machine learning (ML) versus classical statistical methods (SM) for the preoperative risk assessment in proctological surgery. We used clinical data from a nationwide audit: the database consisted of 1510 patients affected by Goligher's grade III hemorrhoidal disease who underwent elective surgery. We collected anthropometric, clinical, and surgical data and we considered ten predictors to evaluate model-predictive performance. The clinical target was the complication rate evaluated at 30-days follow-up. Logistic regression and three ML techniques were compared. ML models included a Decision Tree, a Support Vector Machine, and a classification Extreme Gradient Boosting (XGB). These methodologies could be used to develop a surgical risk calculator, which is already used and widespread for other diseases, that could help clinicians to estimate the chance of an unfavorable outcome after surgery.
19-giu-2024
Inglese
PERILLI, MARIAGRAZIA
VISTOLI, FABIO
GIULIANI, ANTONIO
Università degli Studi dell'Aquila
File in questo prodotto:
File Dimensione Formato  
Tesi Romano.pdf

accesso aperto

Dimensione 1.73 MB
Formato Adobe PDF
1.73 MB Adobe PDF Visualizza/Apri

I documenti in UNITESI sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/20.500.14242/160657
Il codice NBN di questa tesi è URN:NBN:IT:UNIVAQ-160657