Prognostic and diagnostic role of peri-operative inflammatory markers in colorectal cancer

Background and objectives: The relationship between chronic inflammation and tumorigenesis has been largely investigated, and tumor-promoting inflammation proposed as an ‘enabling characteristic’ for tumor development. Also, it is increasingly recognized that the outcome of oncological patients depends not only on the intrinsic characteristics of the tumour, but also on the host immune-response and its ability to recognize and destroy tumour cells before escape. The aim of this study was to e...

Identification of diagnostic and predictive morphological and molecular markers in renal tumors

Objectives: Ongoing advances in tumor biology keep expanding the spectrum of renal neoplasms, with more than twenty renal cell carcinoma histotypes recognized in the last WHO classification. Thus, the discovery of novel diagnostic and predictive biomarkers for rarer tumors, such as those belonging to the “molecularly defined category”, is warranted to improve physicians’ ability to recognize and treat these uncommon diseases. Furthermore, even in the most common entities, a noteworthy percent...

Le scuole della cura: una ricerca qualitativa nelle scuole comunali dell'infanzia di Correggio (Reggio Emilia)

La cura è una dimensione essenziale della vita umana, ed in particolare dell’infanzia, ma le politiche educative internazionali in Early Childhood Education and Care (ECEC), soprattutto ove domina una cultura neoliberista, pongono poca attenzione a tale paradigma, relegando la cura ad una posizione di subalternità o interpretandola come prerequisito all’istruzione, in contrasto ad altre prospettive che invece identificano nella cura il modo di essere e di agire nei contesti educativi volti al...

La produzione ceramica veneta. Manifatture, artigiani e artisti dal 1900 al 1950

La tesi indaga la produzione, specialmente di ambito modernista, prodotta nella prima metà del Novecento in ambito veneto con approfonditi affondi su esposizioni e enti a supporto delle manifatture e artigianato.

Strong@HOME - Development of an innovative technological solution of telemedicine for the prevention, early diagnosis, monitoring and treatment of sarcopenia

Strength, power, and muscle mass are critical variables influencing the quality of daily life during aging. Their decline can lead to impaired motor function, resulting in an increased risk of falls and fractures, cardiovascular and respiratory diseases, cognitive deterioration, and reduced ability to perform everyday activities. This sets off a vicious cycle that may trigger various adverse outcomes, including loss of independence, the need for long-term care, and, in a cascade of events, ev...

Tradition and Evolution of the Iconography of Hell in the Pictorial Cycles of the Alps

This thesis investigates the depiction of Hell in medieval wall paintings across the Alpine regions, spanning from Western Liguria to Friuli-Venezia Giulia, between the late eleventh and fifteenth centuries. Throughout the Middle Ages, visual representations of Hell and the Otherworld in places of worship were designed to engage believers on multiple levels—visually, physically, and emotionally—while reinforcing liturgical messages and moral values. These images served both to illustrate the ...

To (the) brain or not to (the) brain? Distal signaling and non-neural players in brain hyperexcitability.

The brain is a highly dynamic organ whose functions depend on the intricate interplay among neurons, glial cells, endothelial cells, and immune components. Traditionally viewed as the domain of neuronal signaling, emerging evidence underscores the crucial role of the neurovascular unit, where neuronal, glial, vascular, and immune interactions collectively sustain brain health and adaptability. In this study, we explored the modulation of neuronal excitability, a fundamental property underlyi...

“Ogni giorno possiamo trasformare il mondo” Alberto Manzi e l’educazione popolare ed esperienziale con le persone adulte analfabete

Von resultativ zu modal: Das verbale Präfix der- in den südbairischen Varietäten Italiens

The present dissertation concerns the verbal inseparable prefix der-, usually described in the literature on German dialectology as prototypically Bavarian. The derivational morpheme covers a wide range of semantic functions that are prevalently aspectual and often overlap with those of the standard German language, e.g., (d)er-kennen 'recognize', (d/z)er-brechen 'to break something (into pieces)'. Of the many functions of der-, a particular focus is emphasized on its modal semantics, where t...