Algoritmizzazione dei mercati finanziari, abusi di mercato e criteri di imputazione penale all'epoca delle strategie High-Frequency Trading

A Pervasive Healthcare Ecosystem for Monitoring Frail Individuals

Population aging is a global phenomenon marked by increasing life expectancy and declining birth rates, with one in six individuals projected to be aged 60 or over by 2030, and this demographic expected to double to 2.1 billion by 2050. This demographic shift presents significant challenges for healthcare systems, pension sustainability, and social dynamics, particularly as the old-age dependency ratio rises. Additionally, aging populations face a growing prevalence of neurodegenerativ...

Nanocarriers for nutraceutical molecules from sustainable sources: development and characterization

More than one-third of food is wasted alongside the food chain. Despite national policies trying to reduce its production through laws, incentives, sensibilization, and education campaigns, food waste is a persistent issue with notable ethical, environmental, and economic repercussions. Polyphenols are a large class of organic compounds involved in several biological mechanisms. Many experimental studies hint toward their preventive capacity against several non...

Diagnostic, prognostic and predictive significance of the immunohistochemical loss of H3K27me3 in different CNS and extra-CNS tumors

Epigenetic regulation is essential for normal development, influencing critical biological processes such as cell differentiation, tissue development, and responses to environmental factors. The epigenetic signature in cells is a dynamic process changing over time and adapting to internal and environmental stimuli. Dysregulation of these processes is associated with various diseases, including inflammatory and degenerative conditions, as well as cancers. Indeed, several epigenetic changes ha...

A systems-level approach to understanding stromal and neoplastic heterogeneity in PDAC

Escribir en el norte de México. Procesos de fronteriorización en la narrativa de Heriberto Yépez, Luis Humberto Crosthwaite y Rosario Sanmiguel.

La presente ricerca analizza in maniera approfondita la corrente letteraria del Messico settentrionale nota come Literatura de la Frontera Norte o Literatura del Norte. In particolare, l’analisi si concentra sull’area di frontiera tra Messico e Stati Uniti, intesa come uno spazio di intensa significazione e di continua negoziazione identitaria. La frontiera, concepita sia come simbolo che realtà storica, rappresenta un luogo di confronto tra identità, simboli e immaginari divergenti, costitue...

Chronic kidney disease in a population-based cohort: an analytical study of prevalence, dietary patterns, and gene-diet interactions affecting kidney function

La malattia renale cronica (CKD) rappresenta una significativa sfida per la salute pubblica, in cui dieta e predisposizione genetica svolgono un ruolo cruciale nello sviluppo e nella progressione. Tuttavia, le relazioni tra questi fattori e la funzionalità renale sono solo parzialmente comprese, specialmente nel contesto della prevenzione. Questa tesi si propone di affrontare tre obiettivi: (Obiettivo 1) valutare la prevalenza e la consapevolezza della CKD nel distretto della Val Venosta/Vins...

A synoptic digital edition of the Alexanderlied

My doctoral project consists of this dissertation and a scholarly digital edition. In the dissertation, I introduce the context of this work, the scientific motivations that made it necessary, the object of study, the methodology, and the potential of this research. In the digital edition, I present data, metadata, and critical commentary that resulted from philological work in combination with the principles of digital scholarly editing. The topic of my PhD thesis is the Alexanderlied, a Mi...

Development of novel downstream fermentation processes for the recovery and valorisation of Volatile Fatty Acids (VFAs)

This PhD research investigates the development and optimisation of integrated systems for the recovery of bio-based volatile fatty acids (VFAs) from organic waste streams, with the aim of bridging the gap between waste management and high-value bio-based production. Addressing critical challenges such as product inhibition, low VFA concentrations and the complex composition of fermentation effluents, the research focuses on the use of innovative recovery technologies to improve process effici...