During the PhD course I have studied poly(amido amine)s based nanostructured systems, that can be considered as part of the huge field of the polymer therapeutics. After a brief intrpduction about polymer therapeutics and a general review concerning poly(amidoamines), the work done during the PhD course is reported, divided in the following main chapters: Kinetic study of PAAs synthesis in organic solvents; Synthesis of new polymeric precursors of PAA-drug or PAA-protein conjugate by disulfide bond; Synthesis of nano-structured PAA-Cholesterol conjugates; Syntesys of cross linked polyplexes for applications in gene delivery; Glass surface functionalization for AFM imaging of lipid systems.
Purpose Tailoring of Bioactive-Biocompatible Polymers as Soluble Drug Carriers and Hydrogels for Drug Delivery Systems
2008
Abstract
During the PhD course I have studied poly(amido amine)s based nanostructured systems, that can be considered as part of the huge field of the polymer therapeutics. After a brief intrpduction about polymer therapeutics and a general review concerning poly(amidoamines), the work done during the PhD course is reported, divided in the following main chapters: Kinetic study of PAAs synthesis in organic solvents; Synthesis of new polymeric precursors of PAA-drug or PAA-protein conjugate by disulfide bond; Synthesis of nano-structured PAA-Cholesterol conjugates; Syntesys of cross linked polyplexes for applications in gene delivery; Glass surface functionalization for AFM imaging of lipid systems.| File | Dimensione | Formato | |
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https://hdl.handle.net/20.500.14242/132052
URN:NBN:IT:UNIPI-132052