NEW STRATEGY IN ORTHOPAEDICS AND IN THE REDUCTION OF SPINAL SURGERY INFECTIONS

Spondylodiscitis, an infection of the intervertebral discs and vertebral bodies, presents significant challenges in treatment, primarily due to the propensity of bacteria to adhere to spinal implants, leading to biofilm formation. This project discusses the innovative use of silver-coated screws and rods in spinal surgery to combat these issues. The antimicrobial properties of silver are well-documented, notably its ability to inhibit bacterial adhesion and biofilm formation on implant surfaces. The utilization of silver extends beyond anti-infective strategies; it also plays a crucial role in inhibiting cellular metabolism and inducing apoptosis in prostate carcinoma cells, highlighting its potential in oncological applications. The study further explores various surgical approaches, including percutaneous and open techniques, emphasizing the importance of integrating advanced materials in spinal surgeries. The deployment of silver-coated hardware in these contexts not only mitigates the risk of post-operative infections but also enhances the overall outcomes of spinal surgeries by reducing the incidence of implant-related complications.

Spondylodiscitis, an infection of the intervertebral discs and vertebral bodies, presents significant challenges in treatment, primarily due to the propensity of bacteria to adhere to spinal implants, leading to biofilm formation. This project discusses the innovative use of silver-coated screws and rods in spinal surgery to combat these issues. The antimicrobial properties of silver are well-documented, notably its ability to inhibit bacterial adhesion and biofilm formation on implant surfaces. The utilization of silver extends beyond anti-infective strategies; it also plays a crucial role in inhibiting cellular metabolism and inducing apoptosis in prostate carcinoma cells, highlighting its potential in oncological applications. The study further explores various surgical approaches, including percutaneous and open techniques, emphasizing the importance of integrating advanced materials in spinal surgeries. The deployment of silver-coated hardware in these contexts not only mitigates the risk of post-operative infections but also enhances the overall outcomes of spinal surgeries by reducing the incidence of implant-related complications. This research underscores the critical role of silver in both orthopedic and oncological paradigms, promoting a dual therapeutic and anti-infective utility. The integration of such innovative materials in surgical practices is pivotal for advancing patient care in complex spinal and oncological conditions, offering a promising outlook for future interventions