The research project is focused on the development and the synthesis of glycoderivatives as potential drug candidates, for therapeutic use, and as molecular tools, for the study of biological processes. The project includes the study of SGLT1 (Sodium-Glucose co-transporter 1), its role in inflammatory processes and the development of potential carbohydrate-based anti-inflammatory agents. Furthermore, new glycoderivatives and glycoconjugates will be synthetized for other potential pharmacological applications such as the targeting of cytotoxic drugs, as novel potential anticancer agents, and for the development of molecular tools to study several biological phenomena.

Glycoderivatives: drug candidates and molecular tools

D'ORAZIO, GIUSEPPE
2013

Abstract

The research project is focused on the development and the synthesis of glycoderivatives as potential drug candidates, for therapeutic use, and as molecular tools, for the study of biological processes. The project includes the study of SGLT1 (Sodium-Glucose co-transporter 1), its role in inflammatory processes and the development of potential carbohydrate-based anti-inflammatory agents. Furthermore, new glycoderivatives and glycoconjugates will be synthetized for other potential pharmacological applications such as the targeting of cytotoxic drugs, as novel potential anticancer agents, and for the development of molecular tools to study several biological phenomena.
6-feb-2013
Inglese
LA FERLA, BARBARA
Università degli Studi di Milano-Bicocca
File in questo prodotto:
File Dimensione Formato  
phd_unimib_058480.pdf

accesso aperto

Dimensione 4.12 MB
Formato Adobe PDF
4.12 MB Adobe PDF Visualizza/Apri

I documenti in UNITESI sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/20.500.14242/172093
Il codice NBN di questa tesi è URN:NBN:IT:UNIMIB-172093