The coupling of the LC system to an Electrospray Ionization Source (ESI) †" Time of Flight (TOF) mass spectrometer detector allowed to analyze the compounds of interest simultaneously in mixtures of up to 10 compounds at the same time thanks to the higher selectivity of m/z ratio. This approach resulted in the development of an MS analytical method 100 times faster than the one traditionally employed in this sort of determinations.
STUDY OF THE MECHANISMS OF DRUG PASSAGE THROUGH BIOLOGICAL BARRIERS AIMED TO OPTIMIZE BIOAVAILABILITY AND/OR BLOOD-BRAIN BARRIER PERMEATION
2016
Abstract
The coupling of the LC system to an Electrospray Ionization Source (ESI) †" Time of Flight (TOF) mass spectrometer detector allowed to analyze the compounds of interest simultaneously in mixtures of up to 10 compounds at the same time thanks to the higher selectivity of m/z ratio. This approach resulted in the development of an MS analytical method 100 times faster than the one traditionally employed in this sort of determinations.File in questo prodotto:
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https://hdl.handle.net/20.500.14242/333371
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URN:NBN:IT:BNCF-333371