The aim of this thesis has been focused to analyze the positive regulation of Myc-mediated transcription by P-TEFb elongation complex, and the negative control exerted by p14ARF onco-suppressor on Myc's transactivation functions. Moreover in a parallel line of research I investigated the p14ARF involvement on Tat-mediated transcriptional transactivation of HIV-1 (Human Immunodeficiency Virus 1)gene.
Positive and negative regulation of Myc-mediated transcription
2008
Abstract
The aim of this thesis has been focused to analyze the positive regulation of Myc-mediated transcription by P-TEFb elongation complex, and the negative control exerted by p14ARF onco-suppressor on Myc's transactivation functions. Moreover in a parallel line of research I investigated the p14ARF involvement on Tat-mediated transcriptional transactivation of HIV-1 (Human Immunodeficiency Virus 1)gene.File in questo prodotto:
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Utilizza questo identificativo per citare o creare un link a questo documento:
https://hdl.handle.net/20.500.14242/339358
Il codice NBN di questa tesi è
URN:NBN:IT:BNCF-339358