Capture-Enhanced Neutron Irradiation as a novel strategy for Alzheimer’s Disease treatment

This PhD thesis work was carried out within the framework of the NECTAR project (NEutron Capture-enhanced Treatment of neurotoxic Amyloid aggRegates), funded by the European Innovation Council under the Horizon 2020 FET Open RIA programme. NECTAR project aims to explore the effectiveness of a Capture-Enhanced Neutron Irradiation (CENI) treatment, exploring the role of the neutron capture reactions on 10B and 157Gd in order to depolymerize β-Amyloid aggregates, one of the main culprits of Alzh...

High-precision theoretical predictions for particle physics at the intensity frontier

The intensity frontier of particle physics explores the existence of a new theory of fundamental interactions through precision measurements at relatively low energies. The design of more precise experiments has to be accompanied by the development of more accurate Monte Carlo event generators for the simulation of the relevant processes. In order to match the experimental precision, such essential tools must include appropriate higher-order radiative corrections. Specifically, the new genera...

LA DURATA RAGIONEVOLE DELLE INDAGINI. TRA EFFICIENZA DEL PROCESSO ED EFFETTIVITÀ DELLE GARANZIE INDIVIDUALI

International jurisdiction over personality rights disputes: a European private international law perspective

Determining which national courts should have the authority to adjudicate cross-border civil law disputes arising from the infringement of personality rights - namely, the right to reputation and the right to privacy - has long been a sensitive and debated issue in legal literature and practice. The challenges in resolving conflicts of jurisdiction over personality rights disputes can be traced to two layers of complexity that specifically characterise torts against personality and set them a...

Innovative co-design practices within housing retrofit and urban space transformation

My thesis investigates the concept of co-design across two different contexts, presented as separate studies. It includes a comprehensive literature review to establish its theoretical foundations and explore dimensions such as shared language, agency, and decision-making. The first study explores alternative narratives for urban space transformation through co-design, focusing on a case study situated in a peripheral area of Pavia. In this university-community partnership, design addresses s...

Il progetto di una maxi-caravan ecologica e off grid per un turismo circolare all’aria aperta

La tesi di ricerca si colloca all’interno del dibattito relativo al turismo all’aria aperta per lo sviluppo sostenibile del prodotto industriale maxi-caravan e intende promuovere l’evoluzione delle strutture ricettive all’aria aperta, capaci di coniugare le esigenze della salvaguardia e della tutela dell’ambiente naturale con la promozione del territorio, attraverso il progetto di un’unità ricettiva ecologica e off grid. La crescente sensibilità verso i temi ecologici della società contempora...

Rethinking dementia prevention in an aging world: from individual-level dementia risk-reduction approach to community-level brain health promotion

Porto-Novo. Histoire urbaine d’une ville vodun, 1724-1874

The Thesis retrace the urban history of Porto-Novo, the official capital of the Republic of Benin, on the period between 1724, the supposed date of foundation, and 1874, the year of the ascension to the throne of the last sovereign of Porto-Novo, King Toffa, during whose reign the country was progressively incorporated into the French colony of Dahomey (1894-1960). The objective of this work is threefold. First, it seeks to provide a chronological reconstruction of this city’s urban and socia...

L’AUTONOMIA PRIVATA PROCEDIMENTALE PER LA RISOLUZIONE STRAGIUDIZIALE DELLE CONTROVERSIE NELLE FORME DELLA MEDIAZIONE E DELLA NEGOZIAZIONE ASSISTITA.

Attualmente, il ricorso alla tutela giurisdizionale è concepito come uno strumento eventuale e residuale, in quanto si consente alle parti di risolvere (o, almeno, tentare di risolvere) la controversia attraverso diversi canali. Ci si riferisce, in particolare, alle strategie di risoluzione delle liti note come Alternative Dispute Resolutions (cosiddette “ADR”), lasciate all’autonomia negoziale delle parti. Si promuove così un modello meno formale di risoluzione delle controversie, attraverso...