Libera Università Vita-Salute San Raffaele di Milano

Libera Università Vita-Salute San Raffaele di Milano: [661] Istituto

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Prodotti della tipologia (ordinati per Data di deposito in Decrescente ordine): 281 a 300 di 661

Mapping genes and pathways changed following ex vivo engineering of hematopoietic stem cells

2015

Role of allelic imbalance in predicting the risk of hepatocellular carcinoma (HCC) recurrence after liver transplantation

2015

Neuronal ADAM17 promotes oligodendrocyte differentiation and central nervous system myelination

2015

Viral characterization and humoral immune response in the setting of primary HIV-1 infection

2011

MR markers of disease pathophysiology in atypical forms of Alzheimerʼs disease and other dementias

2015

The transcription factor Nfix regulates the proper timing of muscle regeneration and the progression of muscular dystrophy

2013

Cellular and molecular mechanisms of bace1 translational control in neurons and astrocytes

2011

Polycystin-1 binds the Par3/aPKC complex to control polarized cell migration and renal tubular morphogenesis

2012

ERK1 MAP kinase antagonizes ERK2 dependent signaling in the control of the neuronal cell survival and striatal neurodegeneration

2011

Functional dissection of protective activity of human chimeric IgG monoclonal antibodies to meningococcal factor H binding protein

2011

Specificity, dynamics and novel properties of human plasma cells

2011

Safety and efficacy of deep repetitive transcranial magnetic stimulation with H-coil in Parkinsonʼs disease

2014

Pathogenic cross-talk between neoplastic plasma cells and bone marrow infiltrating immune cells during disease progression in a mouse model of multiple myeloma

2014

Im sturm der Zeit Alfred Baeumler nella Repubblica di Weimar

2012

Development of highly sensitive advanced methodologies for the identification of minority mutant alleles

2011

Novel insights into leukemia immune escape after allogeneic hematopoietic stem cell transplantation

2013

Miro-1 controls mitochondrial dynamics and regulates lymphocyte adhesion and migration

2012

Endogenous neural precursor cells of the subventricular zone contribute to maintain brain homeostasis and functionality

2013

The role of perk kinase a mouse model of Charcot-Marie-Tooth 1B neuropathy

2012

Analysis of the role of the cytoplasmic tail of P0 glycoprotein in a mouse model of congenital hypomyelination neuropathy

2012

Istituto	Anno di pubblicazione	Titolo	Autore
Libera Università Vita-Salute San Raffaele di Milano	2015	Mapping genes and pathways changed following ex vivo engineering of hematopoietic stem cells	-
Libera Università Vita-Salute San Raffaele di Milano	2015	Role of allelic imbalance in predicting the risk of hepatocellular carcinoma (HCC) recurrence after liver transplantation	-
Libera Università Vita-Salute San Raffaele di Milano	2015	Neuronal ADAM17 promotes oligodendrocyte differentiation and central nervous system myelination	-
Libera Università Vita-Salute San Raffaele di Milano	2011	Viral characterization and humoral immune response in the setting of primary HIV-1 infection	-
Libera Università Vita-Salute San Raffaele di Milano	2015	MR markers of disease pathophysiology in atypical forms of Alzheimerʼs disease and other dementias	-
Libera Università Vita-Salute San Raffaele di Milano	2013	The transcription factor Nfix regulates the proper timing of muscle regeneration and the progression of muscular dystrophy	-
Libera Università Vita-Salute San Raffaele di Milano	2011	Cellular and molecular mechanisms of bace1 translational control in neurons and astrocytes	-
Libera Università Vita-Salute San Raffaele di Milano	2012	Polycystin-1 binds the Par3/aPKC complex to control polarized cell migration and renal tubular morphogenesis	-
Libera Università Vita-Salute San Raffaele di Milano	2011	ERK1 MAP kinase antagonizes ERK2 dependent signaling in the control of the neuronal cell survival and striatal neurodegeneration	-
Libera Università Vita-Salute San Raffaele di Milano	2011	Functional dissection of protective activity of human chimeric IgG monoclonal antibodies to meningococcal factor H binding protein	-
Libera Università Vita-Salute San Raffaele di Milano	2011	Specificity, dynamics and novel properties of human plasma cells	-
Libera Università Vita-Salute San Raffaele di Milano	2014	Safety and efficacy of deep repetitive transcranial magnetic stimulation with H-coil in Parkinsonʼs disease	-
Libera Università Vita-Salute San Raffaele di Milano	2014	Pathogenic cross-talk between neoplastic plasma cells and bone marrow infiltrating immune cells during disease progression in a mouse model of multiple myeloma	-
Libera Università Vita-Salute San Raffaele di Milano	2012	Im sturm der Zeit Alfred Baeumler nella Repubblica di Weimar	-
Libera Università Vita-Salute San Raffaele di Milano	2011	Development of highly sensitive advanced methodologies for the identification of minority mutant alleles	-
Libera Università Vita-Salute San Raffaele di Milano	2013	Novel insights into leukemia immune escape after allogeneic hematopoietic stem cell transplantation	-
Libera Università Vita-Salute San Raffaele di Milano	2012	Miro-1 controls mitochondrial dynamics and regulates lymphocyte adhesion and migration	-
Libera Università Vita-Salute San Raffaele di Milano	2013	Endogenous neural precursor cells of the subventricular zone contribute to maintain brain homeostasis and functionality	-
Libera Università Vita-Salute San Raffaele di Milano	2012	The role of perk kinase a mouse model of Charcot-Marie-Tooth 1B neuropathy	-
Libera Università Vita-Salute San Raffaele di Milano	2012	Analysis of the role of the cytoplasmic tail of P0 glycoprotein in a mouse model of congenital hypomyelination neuropathy	-

Prodotti della tipologia (ordinati per Data di deposito in Decrescente ordine): 281 a 300 di 661

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Studying immunometabolic alterations in age-related diseases

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VALIDATION OF ARTIFICIAL EPIGENETIC SILENCER TO REDUCE GLIOBLASTOMA IN IMMUNOCOMPETENT MOUSE MODEL

Glioblastoma (GBM) is the most aggressive primary brain tumor in adults and remains associated with extremely poor prognosis despite multimodal treatment, including surgery, radiotherapy, and chemotherapy. The limited efficacy of current therapies reflects key features of this malignancy, including marked inter- and intra-tumoral heterogeneity, highly infiltrative growth, and the strong influence of the tumor microenvironment on disease progression and therapeutic response. In particular, the...

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Terapia genica tramite editing con HDR su cellule staminali emopoietiche

Svelare l’impatto del microbiota sulla fibrosi intestinale: nuove prospettive per la patogenesi e il trattamento delle complicanze associate al morbo di Crohn.

Complicanze fibrotiche della malattia di Crohn

Lo standard setting delle organizzazioni internazionali per la Pubblica Amministrazione nell'epoca della fine dell'ordine globale neoliberale

La tesi analizza l'impatto dello standard setting delle organizzazioni internazionali (in particolare delle Nazioni Unite) per la pubblica amministrazione nell'attuale scenario di fine dell'ordine globale neoliberale.

REFORMING COMMUNICATION IN PUBLIC ADMINISTRATION: A RESEARCH ON INCLUSIVE LANGUAGE

Linguaggio inclusivo di genere

Proliferative stress and DNA damage response pathways in hematopoietic stem cell gene therapy and clonal hematopoiesis

Gene editing (GE) of hematopoietic stem and progenitor cells (HSPCs) holds significant therapeutic promise but remains constrained by genotoxic risks associated with DNA double-strand breaks, donor template delivery, and proliferation-induced stress during ex vivo manipulation. Ex vivo culture is indispensable to achieve efficient homology-directed repair (HDR), yet comes at the cost of inducing cellular stress and compromising HSPC fitness. Here, we identify p38 MAPK signaling as a central r...

Studying human Hematopoietic Stem/Progenitor Cells Trafficking in vivo

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Unraveling the role of the alarmin HMGB1 in the ageing process

High Mobility Group Box 1 (HMGB1) is a nuclear protein that, in physiological conditions, is predominantly localized in the nucleus. Upon cellular stress, it can translocate to the cytosol and can be released extracellularly, where it regulates tissue regeneration and inflammatory responses in a redox-state-dependent manner. HMGB1 bioactivities has been associated with several hallmarks of aging, and HMGB1 has been recently proposed as a biomarker of frailty. Here we hypothesized that aging p...

Unravelling the role of Integrated Stress Response signalling in metastatic Breast Cancer bioenergetics

The Integrated Stress Response (ISR) is an evolutionarily conserved adaptive pathway that mediates translation reprogramming in response to microenvironmental stress, often hijacked by cancer cells to promote metastasis. To reveal novel targetable vulnerabilities in Triple-negative Breast Cancer (TNBC), the most aggressive breast cancer subtype, characterized by high metastatic propensity and limited therapeutic options, here we elucidate the mechanisms by which ISR accommodates the energy de...

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