Computational approaches to the investigation of proteins involved in Parkinson's Disease

Parkinson's disease (PD) is the second most spread neurodegenerative disease (after Alzheimer's). It is a disease for which there is currently no cure. The average age of onset is 60 years, and the prevalence rises significantly from 0.3% in the entire population to about 1% in people over 60 years old and up to 5% in over 85 years old [1, 2]. However, about 5 to 10 % of people with PD have "early-onset" disease that begins before the age of 50 [34, 35, 36]...