Study of green reactions for sustainable organic synthesis

Recent advances in organic synthesis have contributed significantly to enhancing human quality of life but have also caused serious environmental pollution. In response, global research has increasingly shifted towards greener and more sustainable practices, in line with principles of green chemistry. To tackle current social and environmental challenges, there is an increasing focus on the development of new materials, particularly the exploration of biomaterials as sustainable alternatives to conventional resources. In this context, biopolymers have attracted significant attention in catalysis due to their inherent availability, exceptional chemical efficiency, and desirable properties such as biodegradability, biocompatibility, and non-toxicity. Silk fibroin (SF), an attractive natural fibrous protein extracted from Bombyx mori silkworm cocoons, has emerged as a highly promising biomaterial owing to its accessibility, physical-chemical properties, and adaptability. Besides the traditional use in textile industry, SF is recognized as a versatile material that has been investigated as an encouraging resource in biomedicine, optoelectronics and many other technological applications. In this context, this PhD thesis focuses on the application of SF, a sustainable and versatile biopolymer, in the field of green catalysis. The untapped potential and versatility of SF as a heterogeneous green catalyst was explored, as well as its efficacy as support for iron catalysis. By highlighting the potential of biopolymers, specifically SF, as effective and sustainable alternatives to conventional synthetic supports and traditional catalysts, this research addresses key challenges associated with catalyst preparation complexity. Overall, the findings contribute to the expanding field of sustainable catalysis, emphasizing the role of SF in promoting greener and more efficient chemical processes.