An innovative preparation technique, to transform autologous teeth into graft material suitable for regeneration procedures in different areas of oral surgery

Regenerative medicine is based on the science of applied biomaterials. Biomaterials have a strong impact on patient care to improve the quality of life. Absorbable materials have recently been needed in the field of oral hard tissue engineering1 . Tooth extraction is one of the most common procedures in dentistry, with almost all teeth extracted considered as clinical waste and therefore discarded. It is known that the alveolar process is a structure depending on the tooth, its volume and shape are controlled by the shape, axis and inclination of the teeth2 . The use of extracted permanent teeth as grafting materials has been proposed since 1967, when Yeomans and Urist3 and Bang and Urist4 demonstrated osteoinduction properties of the autogenous demineralized dentin matrix; a few years later, Kawai and Urist partially purified bone morphogenetic proteins of the bovine dentine matrix5 . The idea of using the autologhous tooth as a bone substitute in the grafting procedure started with a similar chemical composition between bone and dentin (6).The aim of this study is to test an innovative medical device capable of obtaining dental graft materials starting from the tooth of the patient. The second outcome is to evaluate the tooth extracted as autologous tooth graft used for socket preservation followed by histological analysis.