Studio, formulazione e stabilizzazione di bioattivi da sottoprodotti vegetali di filiera alimentare

This doctoral dissertation investigates the sustainable valorization of berry pomace, a nutrient-rich by-product of the agri-food industry in the Piedmont region, with a focus on blueberry and raspberry residues. Utilizing advanced green technologies such as enzymatic treatments and microwave-assisted extraction (MAE), the study demonstrates the potential of these by-products as valuable sources of bioactive compounds—including phenolics, oligosaccharides, polyunsaturated fatty acids, tocopherols, and squalene. These substances exhibit antioxidant, prebiotic, and functional properties, positioning them as promising ingredients for the nutraceutical, food, cosmetic, and pharmaceutical sectors.The research emphasizes circular bioeconomy principles, transforming what is typically considered waste into high-value resources. Enzymatic treatments notably enhanced the extraction of phenolics and oligosaccharides from blueberry pomace, while MAE efficiently recovered bioaccessible antioxidant compounds from raspberry pomace. In vitro studies confirmed the bioactivity and functional relevance of these extracts.Key challenges addressed include compositional variability of pomace and the scalability of green technologies. The project also considers regulatory and market barriers to industrial integration, advocating for multi-stakeholder collaboration to advance sustainable innovation.Conducted in partnership with Ponti S.p.A. and supported by international collaborations, this work bridges academic research and industrial application. It offers practical frameworks for eco-efficient production and waste reduction, contributing to the broader transition toward a circular and sustainable agri-food system.