UNITesi

Università degli Studi del Piemonte orientale "Amedeo Avogadro": [579] Istituto

Sfoglia
Prodotti della tipologia (ordinati per Data di deposito in Decrescente ordine): 1 a 20 di 579
Istituto Anno di pubblicazione Titolo Autore file(s)
Università degli Studi del Piemonte orientale "Amedeo Avogadro" 2025 Tissue regeneration: preclinical research and therapeutic perspectives -
Università degli Studi del Piemonte orientale "Amedeo Avogadro" 2025 Assessment of preload dependance in critical care: new insights and techniques -
Università degli Studi del Piemonte orientale "Amedeo Avogadro" 2025 Functional ingredients from food wastes: the case-study of cocoa bean shells -
Università degli Studi del Piemonte orientale "Amedeo Avogadro" 2025 Leveraging advanced technologies to optimize in vitro biophysical stimulation experiments -
Università degli Studi del Piemonte orientale "Amedeo Avogadro" 2025 Novel mass-spectrometry approaches to decode molecular mechanisms and therapeutic targets in rare diseases: insights into soft-tissue sarcoma, mucosal melanoma and amyotrophic lateral sclerosis -
Università degli Studi del Piemonte orientale "Amedeo Avogadro" 2025 Developing a mushroom supply chain for food purposes in the European perspective: companies’ competitiveness and consumer behaviour -
Università degli Studi del Piemonte orientale "Amedeo Avogadro" 2025 Long-term results of the Fondazione Italiana Linfomi (FIL) MCL0208 trial of lenalidomide maintenance versus observation after Autologous Stem Cell Transplantation (ASCT) in Mantle Cell Lymphoma (MCL) patients -
Università degli Studi del Piemonte orientale "Amedeo Avogadro" 2025 Formulation, characterisation and application of microencapsulated systems for pharmaceutical and food purposes -
Università degli Studi del Piemonte orientale "Amedeo Avogadro" 2025 Tutela dell’ambiente e assetto costituzionale: fonti del diritto, forma di stato e rapporti ordinamentali. Nuove dinamiche alla luce della legge costituzionale n. 1/20222 -
Università degli Studi del Piemonte orientale "Amedeo Avogadro" 2025 Sustainable and innovative strategies for the discovery of new therapeutic agents -
Università degli Studi del Piemonte orientale "Amedeo Avogadro" 2025 Terpenes: from biodiversity to chemical diversity and bioactivity -
Università degli Studi del Piemonte orientale "Amedeo Avogadro" 2025 Development and characterization of new metal-based nanosystems as diagnostic probes for molecular imaging -
Università degli Studi del Piemonte orientale "Amedeo Avogadro" 2025 Massively parallel reporter assay (MPRA) combined with bayesian fine mapping approaches prioritize variants associated with multiple sclerosis (MS) from genome wide association studies (GWAS) with a potential functional role and interaction with environmental factors -
Università degli Studi del Piemonte orientale "Amedeo Avogadro" 2025 Unraveling the role of nicotinamide phosphoribosyltransferase (NAMPT) in triple-negative breast cancer: insights into metastatic dynamics -
Università degli Studi del Piemonte orientale "Amedeo Avogadro" 2025 Spray drying: process development and optimization for the production of pharmaceutical powders -
Università degli Studi del Piemonte orientale "Amedeo Avogadro" 2025 Green methodologies for the synthesis and use of isocyanides and their application in medicinal chemistry -
Università degli Studi del Piemonte orientale "Amedeo Avogadro" 2025 Development of multidentate ligands selective for metal ions used in diagnostic or theranostic imaging -
Università degli Studi del Piemonte orientale "Amedeo Avogadro" 2025 Integration of [18F]FDG-PET radiomics with liquid biopsy improves outcome prediction in newly diagnosed DLBCL patients -
Università degli Studi del Piemonte orientale "Amedeo Avogadro" 2025 La tutela ambientale dell’impresa agro-alimentare. Tra sanzione, prevenzione e riparazione -
Università degli Studi del Piemonte orientale "Amedeo Avogadro" 2025 Innovative approaches to Herpes Simplex virus treatment using natural products -
Prodotti della tipologia (ordinati per Data di deposito in Decrescente ordine): 1 a 20 di 579
Legenda icone

  •  file ad accesso aperto
  •  file disponibili sulla rete interna
  •  file disponibili agli utenti autorizzati
  •  file disponibili solo agli amministratori
  •  file sotto embargo
  •  nessun file disponibile

Prodotti recenti

Tissue regeneration: preclinical research and therapeutic perspectives

Continuous advancements in healthcare and the resulting increase in life expectancy have led to a rise in chronic and degenerative diseases, highlighting the need for innovative therapeutic approaches. Among these, tissue regeneration has emerged as a promising strategy to restore and enhance the functionality of damaged tissues, particularly in conditions affecting musculoskeletal health. Tissue regeneration encompasses diverse approaches, including the use of bioactive molecules to stimulat...

Assessment of preload dependance in critical care: new insights and techniques

Fluid administration is a cornerstone in the management of hemodynamic instability, aimed at increasing cardiac output (CO) and improving tissue perfusion. However, only half of critically ill patients experience a meaningful rise in CO after fluid loading, underscoring the importance of identifying preload responsiveness to avoid unnecessary or harmful volume expansion. Traditional fluid challenges (350–500 ml) represent treatments rather than diagnostic tools, prompting the investigation of...

Functional ingredients from food wastes: the case-study of cocoa bean shells

The valorisation of food by-products is a promising strategy for sustainability within the circular economy. Cocoa bean shells (CBSs), a by-product of the cocoa production chain, are a waste rich in bioactive compounds, including polyphenols, dietary fibres and lipids. This thesis investigates innovative approaches to convert CBSs into functional ingredients for food and nutraceutical applications. Key findings include improving the fermentability of CBSs through enzymatic treatments, which e...

Leveraging advanced technologies to optimize in vitro biophysical stimulation experiments

This thesis investigates the impact of biophysical stimuli on bone tissue regeneration using advanced in vitro models. Chapter 1: Introduces a novel bioreactor combining fluid flow shear stress and pulsed electromagnetic fields (PEMF) for 3D bone tissue culture. Computational simulations optimize the system, and preliminary experiments with human bone marrow-derived mesenchymal stem cells (hBMSCs) assess the osteogenic potential of these stimuli. Chapter 2: Develops 3D-printed polylactic acid...

Novel mass-spectrometry approaches to decode molecular mechanisms and therapeutic targets in rare diseases: insights into soft-tissue sarcoma, mucosal melanoma and amyotrophic lateral sclerosis

In the present PhD thesis mass-spectrometry-based approaches were used to identify putative biomarkers and therapeutic targets for uncurable rare diseases including Soft-tissue Sarcoma (STS), Mucosal melanoma (MM) and Amyotrophic lateral sclerosis (ALS). The present work allowed the identification of novel biological insights on these diseases. The thesis is divided into three main chapters. The first study focused on soft-tissue sarcoma. Our results provided new biological information on the...

Developing a mushroom supply chain for food purposes in the European perspective: companies’ competitiveness and consumer behaviour

In the context of evolving global food systems, sustainable and health-conscious dietary practices are increasingly essential. Mushrooms and mushroom-based products have garnered attention due to their nutritional value, low resource requirements, and potential as sustainable meat alternatives. Despite their growing importance, research on the edible mushroom supply chain remains limited. This thesis investigates the mushroom industry in Italy and consumer behaviors surrounding mushrooms and ...

Long-term results of the Fondazione Italiana Linfomi (FIL) MCL0208 trial of lenalidomide maintenance versus observation after Autologous Stem Cell Transplantation (ASCT) in Mantle Cell Lymphoma (MCL) patients

The FIL MCL0208 phase III study compared lenalidomide maintenance (LEN) for 2 years to observation (OBS) after autologous stem cell transplantation in young (age <65 years) patients with previously untreated mantle cell lymphoma. LEN resulted in superior progression-free survival (PFS) but no overall survival (OS) benefit. The trial included a large minimal residual disease (MRD) sub-study, which was limited at early detection time points but highlighted the high prognostic value of both p...

Formulation, characterisation and application of microencapsulated systems for pharmaceutical and food purposes

This thesis describes the formulation, production and characterisation of different microencapsulated systems for pharmaceutical and food purposes. Several microencapsulation techniques (ionotropic gelation, spray drying, spray congealing, microfluidics, and solvent evaporation) were investigated. Ionotropic gelation was selected for the microencapsulation of Artemisia absinthium L. ethanolic extract and vitamin D oily solution into alginate-based microspheres destined to be an innovative ing...

Tutela dell’ambiente e assetto costituzionale: fonti del diritto, forma di stato e rapporti ordinamentali. Nuove dinamiche alla luce della legge costituzionale n. 1/20222

Il diritto dell'ambiente costituisce un esempio paradigmatico di sistema multilivello delle fonti. Se il pluralismo normativo garantisce risposte flessibili alle sfide ambientali, tuttavia comporta delle criticità in termini di certezza del diritto. La legge costituzionale 11 febbraio 2022, n. 1, introducendo la tutela dell'ambiente, degli ecosistemi e della biodiversità tra i principi fondamentali della Costituzione, rappresenta una svolta significativa rispetto alla possibilità di ridefinir...

Sustainable and innovative strategies for the discovery of new therapeutic agents

During my PhD, I integrated green chemistry principles to develop sustainable and efficient methods for synthesizing biologically active compounds. In collaboration with Nerviano Medical Sciences, I focused on metal-free visible-light photocatalysis to enable radical coupling reactions: Synthesis of a-halocarbonyl derivatives via a Giese-type photoredox process, yielding intermediates converted into amino esters, heterocycles, and cinnamic derivatives. This strategy facilitated the synthesis...

Scopri
Istituto
  • Università degli Studi del Piemon...579
Data di pubblicazione
  • 2020 - 2025240
  • 2010 - 2019270
  • 2000 - 200968
  • 1997 - 19991
Settore disciplinare
  • Settore MED/04 - Patologia Generale46
  • Settore BIO/10 - Biochimica28
  • Settore BIO/14 - Farmacologia23
  • Settore MED/15 - Malattie del Sangue22
  • Settore CHIM/03 - Chimica General...19
  • Settore MED/07 - Microbiologia e ...16
  • Settore CHIM/06 - Chimica Organica15
  • Settore MED/50 - Scienze Tecniche...14
  • Settore BIO/13 - Biologia Applicata13
  • Settore CHIM/01 - Chimica Analitica13
Accesso al fulltext
  • no fulltext276
  • open199
  • embargoed57
  • internalNetwork35
  • reserved8
  • mixed2
  • partially open2