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Università degli Studi del Piemonte orientale "Amedeo Avogadro": [513] Istituto

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Prodotti della tipologia (ordinati per Data di deposito in Decrescente ordine): 1 a 20 di 513
Istituto Anno di pubblicazione Titolo Autore file(s)
Università degli Studi del Piemonte orientale "Amedeo Avogadro" 2024 From risk to prevention: nutrition and early biomarker discovery in autoimmune diseases -
Università degli Studi del Piemonte orientale "Amedeo Avogadro" 2024 Reactive oxygen species: a merging solution for two unmerging problems -
Università degli Studi del Piemonte orientale "Amedeo Avogadro" 2024 Linear, stellar and hyperbranched copolymers with amphiphilic nature -
Università degli Studi del Piemonte orientale "Amedeo Avogadro" 2024 Sarcopenia: potential new tools to face a giant -
Università degli Studi del Piemonte orientale "Amedeo Avogadro" 2024 A serious game for surgical endoscopy: an innovative virtual reality simulator to democratize endoscopic training -
Università degli Studi del Piemonte orientale "Amedeo Avogadro" 2024 Discovery and development of small molecules, prodrugs and PROTACs: the role of a modular and reliable chemistry -
Università degli Studi del Piemonte orientale "Amedeo Avogadro" 2024 Biomaterials for bone regeneration possessing novel antibacterial and anti-inflammatory properties: comprehensive biological evaluations -
Università degli Studi del Piemonte orientale "Amedeo Avogadro" 2024 A phase 3 study of pelebresib plus ruxolitinib for JAK inhibitor-naive patients with myelofibrosis -
Università degli Studi del Piemonte orientale "Amedeo Avogadro" 2024 Immune system activity in Type 1 Diabetes at the onset: data of MINDFUL project -
Università degli Studi del Piemonte orientale "Amedeo Avogadro" 2024 Role of lung ultrasonography in critically ill patients -
Università degli Studi del Piemonte orientale "Amedeo Avogadro" 2024 Multi-omics approach to study complex diseases: a monozygotic discordant for ALS twin pair study and Pedigree project -
Università degli Studi del Piemonte orientale "Amedeo Avogadro" 2024 Molecular clustering and fragmentomics on circulating tumor DNA improve outcome prediction in diffuse large B cell lymphoma -
Università degli Studi del Piemonte orientale "Amedeo Avogadro" 2024 Lifestyle, demographic and psychological factors involved in the choice and willingness to pay for functional and healthy foods: consumers’ preferences and behaviour -
Università degli Studi del Piemonte orientale "Amedeo Avogadro" 2024 From in vitro probiotic strain selection and beyond -
Università degli Studi del Piemonte orientale "Amedeo Avogadro" 2012 test -
Università degli Studi del Piemonte orientale "Amedeo Avogadro" 2024 Exploring the role of lactobacilli in heavy metal detoxification: a journey from lab to gut -
Università degli Studi del Piemonte orientale "Amedeo Avogadro" 2024 Preserving vascular stability: FVIII's influence on endothelial cells -
Università degli Studi del Piemonte orientale "Amedeo Avogadro" 2024 Metabolic diseases and their link with lifestyle and gut microbiota: an overview from pediatric age to adults -
Università degli Studi del Piemonte orientale "Amedeo Avogadro" 2024 Lifestyle Medicine for Longevity (LSM4Long) pragmatic randomized controlled trial: development and implementation of a combined lifestyle intervention for older people in Long-Term Care -
Università degli Studi del Piemonte orientale "Amedeo Avogadro" 2024 Immunocompatibility of metallic-ion doped bioactive glasses and titanium-based implants for musculoskeletal regeneration -
Prodotti della tipologia (ordinati per Data di deposito in Decrescente ordine): 1 a 20 di 513
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Prodotti recenti

From risk to prevention: nutrition and early biomarker discovery in autoimmune diseases

The overarching goal of the Ph.D. project is to investigate the relationship between dietary habits and immune cell perturbations and to find new early disease biomarkers, in the context of MINDFUL (Microvesicles at the Intersection between Autoimmune Diseases, Food, and Unhealthy Lifestyles) project. The exploration of diet as a protective/risk factor for AD started from the development of innovative nutritional epidemiology tools and large database interrogation. Literature reviews undersc...

Reactive oxygen species: a merging solution for two unmerging problems

Malignant mesothelioma is a rare cancer arising from the serosal surfaces of the body, mainly from the pleural layer. The primary cause of pleural mesothelioma is exposure to asbestos fibers, a group of naturally occurring fibrous minerals with excellent physical and electrochemical insulating properties and a long history of industrial applications. Despite a progressive ban on asbestos production and usage in over 50 countries worldwide since the 1980s, the incidence of pleural mesothelioma...

Linear, stellar and hyperbranched copolymers with amphiphilic nature

Amphiphilic copolymers have distinct hydrophobic and hydrophilic segments in their structure. This unique molecular arrangement gives amphiphilic copolymers the ability to self-assemble in suitable solvents to form a variety of nanostructures such as micelles, vesicles or nanoparticles. Solvophobic regions align in a core structure to minimise contact with the solvent, while solvophilic segments interact favourably to form an outer layer that stabilises the nanostructure. The use of controlle...

Sarcopenia: potential new tools to face a giant

Sarcopenia, the age-related decline in muscle mass and functionality associated with poor physical performance, physical disability, and increased mortality, significantly impacts the quality of life in the elderly. While physical exercise is the only effective intervention, it is not always feasible for advanced-stage patients. Thus, the discovery and development of novel approaches to tackle age-related muscle loss are becoming increasingly urgent. Although Vitamin D (VD) deficiency is asso...

A serious game for surgical endoscopy: an innovative virtual reality simulator to democratize endoscopic training

Background: Training on virtual reality simulators (VRS) is effective, shortening the learning curve to competency. However, current simulators are expensive and difficult to access. Low-cost portable VRS could help democratize and standardize endoscopic training. To meet this need, a novel, portable, gamified VRS- Rescue in the Deep (RID)- was developed. Our goal was to assess and validate the efficacy of RID in endoscopic skills assessment. Methods: A randomized comparative trial was perfor...

Discovery and development of small molecules, prodrugs and PROTACs: the role of a modular and reliable chemistry

Drug discovery is an ever-evolving process, driven by the identification of potential disease targets and the emergence of novel technologies and synthetic strategies. In this context, my doctoral research encompasses the development of small molecules (prodrugs and dual targeting inhibitors) and protein degraders (PROTACs) as therapeutic approaches for different diseases, including ultra-rare genetic diseases, autoimmunity, and cancer. To access these compounds, I explored various synthetic...

Biomaterials for bone regeneration possessing novel antibacterial and anti-inflammatory properties: comprehensive biological evaluations

Bone fractures, a common global injury due to trauma, particularly for those with osteoporosis, cause a significant economic burden. Often caused by falls, accidents, or sports, they are frequently treated by healthcare professionals. While the body can heal minor fractures naturally, severe injuries like spinal cord or bone damage might require regenerative surgery. However, this healing ability weakens with age and factors like inflammation from damaged tissue. Implants, widely used in surg...

A phase 3 study of pelebresib plus ruxolitinib for JAK inhibitor-naive patients with myelofibrosis

Background Current treatment strategies in myelofiboris are based on Janus kinase (JAK) inhibitors. Unfortunately, these treatments provide limited depth and durability of response. A potential new treatment paradigm is the combination of novel agents targeting different patways with the current used JAK inhibitors. Herein we present the results of a randomized clinical trial comparing pelabresib, a bromodomain and extraterminal domain (BET) inhibitor, plus ruxolitinib, to placebo plus ruxoli...

Immune system activity in Type 1 Diabetes at the onset: data of MINDFUL project

Background. The onset of type 1 diabetes (T1D) has been associated with altered frequency and phenotype of both innate and adaptive immune cells. Furthermore, an altered frequency or function of extracellular vesicles (EVs) could be implicated in the onset of the disease. EVs are small particles released into biological fluids by all cells and play an important role in intracellular communication. Our primary aim is to characterize the immune system and microvesicles involved in children and ...

Role of lung ultrasonography in critically ill patients

Initially a qualitative diagnostic tool, lung ultrasound (LUS) has transformed into a quantitative method with the development of scoring systems that correlate ultrasound findings with lung density. These systems enhance the ability to grade lung aeration, quantify disease severity, and monitor disease progression and treatment response. This research explored the quantitative aspects of LUS through three projects: 1 Review on Quantitative Techniques: This article reviewed various quantitati...

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Istituto
  • Università degli Studi del Piemon...513
Data di pubblicazione
  • 2020 - 2025174
  • 2010 - 2019270
  • 2000 - 200968
  • 1997 - 19991
Settore disciplinare
  • Settore MED/04 - Patologia Generale40
  • Settore BIO/10 - Biochimica26
  • Settore BIO/14 - Farmacologia21
  • Settore CHIM/03 - Chimica General...18
  • Settore MED/15 - Malattie del Sangue18
  • Settore BIO/13 - Biologia Applicata13
  • Settore CHIM/06 - Chimica Organica13
  • Settore MED/07 - Microbiologia e ...13
  • Settore CHIM/01 - Chimica Analitica12
  • Settore CHIM/02 - Chimica Fisica11
Accesso al fulltext
  • no fulltext268
  • open161
  • embargoed37
  • internalNetwork35
  • reserved8
  • mixed2
  • partially open2