Within the range of the Virtual Biophysics Lab tumour growth numerical simulator, this work aims to develop a mathematical model able to describe the cell cycle desynchronization observed in the cell populations and the effects of DNA damage and repair due to ionizing radiation. Following a review of the already available models, some other original ones are proposed; one of these has been also tested on tumour cells by means of cytometry: the results of the related data analysis are not yet conclusive.
MODELS OF DNA DAMAGE, REPAIR, AND MISREPAIR
2015
Abstract
Within the range of the Virtual Biophysics Lab tumour growth numerical simulator, this work aims to develop a mathematical model able to describe the cell cycle desynchronization observed in the cell populations and the effects of DNA damage and repair due to ionizing radiation. Following a review of the already available models, some other original ones are proposed; one of these has been also tested on tumour cells by means of cytometry: the results of the related data analysis are not yet conclusive.File in questo prodotto:
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Utilizza questo identificativo per citare o creare un link a questo documento:
https://hdl.handle.net/20.500.14242/266776
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URN:NBN:IT:UNITS-266776