This work presents results on the computed electromagnetic field within isolated mitochondria when exposed to near-infrared illuminations concerning photobiomodulation experiments. The accuracy of the electromagnetic models implemented for dosimetry is important. The mechanism of interaction of light with these organelles is still unclear, so it is important to improve our knowledge with reliable simulations and experiments. To obtain such results, we present several models. Although they refer to a well-defined experimental setup, the different models must consider the different possible arrangements of the mitochondria and the differences in their dimensions and constitutive parameters. Different wavelengths and polarizations are considered too. The effects of all the parameters on the electromagnetic field inside the mitochondria and the internal morphology are studied. Computational techniques are also exploited to find reliable approximations of the solutions of problems involving moving objects. The effect of the motion of objects on the electromagnetic field is studied as well; for this type of problem, it is necessary to understand that the constitutive relations are modified because the movement makes any material to appear as a bianisotropic medium. In particular, the rotation movement of symmetrical bodies is studied, the electromagnetic field is calculated and an inversion algorithm for the estimate of the rotation speed is proposed.

Electromagnetic modeling and simulations of interest for low-level laser therapies or for problems involving moving objects

CLEMENTE VARGAS, MARIO RENE
2023

Abstract

This work presents results on the computed electromagnetic field within isolated mitochondria when exposed to near-infrared illuminations concerning photobiomodulation experiments. The accuracy of the electromagnetic models implemented for dosimetry is important. The mechanism of interaction of light with these organelles is still unclear, so it is important to improve our knowledge with reliable simulations and experiments. To obtain such results, we present several models. Although they refer to a well-defined experimental setup, the different models must consider the different possible arrangements of the mitochondria and the differences in their dimensions and constitutive parameters. Different wavelengths and polarizations are considered too. The effects of all the parameters on the electromagnetic field inside the mitochondria and the internal morphology are studied. Computational techniques are also exploited to find reliable approximations of the solutions of problems involving moving objects. The effect of the motion of objects on the electromagnetic field is studied as well; for this type of problem, it is necessary to understand that the constitutive relations are modified because the movement makes any material to appear as a bianisotropic medium. In particular, the rotation movement of symmetrical bodies is studied, the electromagnetic field is calculated and an inversion algorithm for the estimate of the rotation speed is proposed.
2-mar-2023
Inglese
RAFFETTO, MIRCO
VALLE, MAURIZIO
Università degli studi di Genova
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/20.500.14242/65759
Il codice NBN di questa tesi è URN:NBN:IT:UNIGE-65759