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Università degli Studi di Genova: [2801] Istituto

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Prodotti della tipologia (ordinati per Data di deposito in Decrescente ordine): 1 a 20 di 2.801
Istituto Anno di pubblicazione Titolo Autore file(s)
Università degli Studi di Genova 2025 Multiple Latent Variable Generative Models: an Information-Theoretic Perspective and Applications -
Università degli Studi di Genova 2025 Perception and Navigation in the Absence of Vision: Developing Assistive Technologies for Environmental Awareness in the Blind -
Università degli Studi di Genova 2025 Engineering the blood-brain barrier: molecular approaches for the modulation of tight junctions -
Università degli Studi di Genova 2025 Targeting oxidative stress and inflammation in retinal degeneration with Platinum Nanozymes -
Università degli Studi di Genova 2025 Brain Mechanisms of Genetic and Inflammatory Double-Hit Vulnerability to Developmental Social Dysfunctions -
Università degli Studi di Genova 2025 Negr1 upregulation converges into core impaired processes in autism spectrum disorders: from pathophysiology to potential therapeutic target -
Università degli Studi di Genova 2025 Contribution of multiple sensory modalities to texture discrimination in head-fixed mice -
Università degli Studi di Genova 2025 Improving Transparency, Trust, and Automation in the Software Supply Chain -
Università degli Studi di Genova 2025 A Reinforcement Learning Framework for Real-Time Multi-Agent Manipulation Control of Collaborative Robots -
Università degli Studi di Genova 2025 Multi-scale Molecular Modeling and Simulations of Voltage-Gated Sodium Channels and their Modulation by the Proline-Rich Transmembrane Protein 2 (PRRT2) -
Università degli Studi di Genova 2025 Optimization and Learning-Based Planning and Control for Quadrupedal Manipulators -
Università degli Studi di Genova 2025 Enhancing State Estimation in Quadruped Robots: Multi-Sensor Fusion for Challenging Terrains -
Università degli Studi di Genova 2025 Autonomous Loco-Manipulation for Hybrid Wheeled-Legged Robots in Cluttered and Unknown Environments -
Università degli Studi di Genova 2025 Functional mapping of BLA and CA3 Dendritic Synaptic Inputs in CA1 Pyramidal Neurons of the Ventral Hippocampus -
Università degli Studi di Genova 2025 Evaluation of the wind hazard and risk during high-impact weather conditions on the natural and built environment in Liguria -
Università degli Studi di Genova 2025 Development of Fragility curves for the Seismic Risk Assessment of a School Buildings Portfolio at Regional scale -
Università degli Studi di Genova 2025 Assessment of papillary and macular blood flow by OCT Angiography: a comparative study in healthy subjects and patients with different optic neuropathies -
Università degli Studi di Genova 2025 mGlu5 receptor negative allosteric modulation reduces the aberrant cellular reactivity and neurotoxicity of iNPCs-derived human astrocytes differentiated from ALS patients -
Università degli Studi di Genova 2025 Derangement of ATP- and NAD+- related pathways in α-sarcoglycanopathy: identification of new therapeutic strategies -
Università degli Studi di Genova 2025 Inter-Subject Variability in Clinical Response to Elexacaftor/Tezacaftor/Ivacaftor Therapy: The Role of Therapeutic Drug Monitoring -
Prodotti della tipologia (ordinati per Data di deposito in Decrescente ordine): 1 a 20 di 2.801
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Prodotti recenti

Multiple Latent Variable Generative Models: an Information-Theoretic Perspective and Applications

In recent years, the field of image generation has made significant advancements, as modern deep learning systems became capable of producing photo-realistic pictures of stunning quality. In the vast amount of possible architectures that can perform such a task, we recognize an emerging subclass, which we term Multiple Latent Variable Generative Models (MLVGMs). These systems, developed as an improvement over traditional latent variable frameworks such as Variational Autoencoders (VAEs) and G...

Perception and Navigation in the Absence of Vision: Developing Assistive Technologies for Environmental Awareness in the Blind

Spatial navigation allows people to navigate their surroundings efficiently, and it is one of the most important aspects of daily life. To understand the spatial navigation of blind people, my PhD focused on cognitive processes that underlie the navigation of blind and visually impaired people, paying special attention to auditory perception, path integration, and environmental learning. Moreover, my PhD also looks at the multisensory mechanism that helps efficient spatial navigation, which e...

Engineering the blood-brain barrier: molecular approaches for the modulation of tight junctions

The blood-brain barrier (BBB) is a multicellular structure comprising pericytes, astrocytes, and endothelial cells, which together safeguard the brain parenchyma and preserve its homeostasis. Endothelial cells are the walls of brain capillaries, acting as the first line of defence against the uncontrolled passive diffusion of solutes from the bloodstream. The selective transcellular transport of molecules is facilitated by specific transmembrane transporters, while the paracellular space betw...

Targeting oxidative stress and inflammation in retinal degeneration with Platinum Nanozymes

The various forms of neurodegeneration stem from a damaging interplay of oxidative stress, neuronal death, and inflammation, which create a pathological cycle responsible for pathological progression. Conditions like retinitis pigmentosa (RP) and age-related macular degeneration (AMD) are linked to these mechanisms in the eye. This study suggests using platinum nanoparticles (PtNPs) that act like antioxidant enzymes, such as catalase and superoxide dismutase, to disrupt this harmful cycle. T...

Brain Mechanisms of Genetic and Inflammatory Double-Hit Vulnerability to Developmental Social Dysfunctions

The 16p11.2 proximal deletion is a copy number variant (CNV) associated with an increased risk of autism spectrum disorders (ASD), though its phenotypic manifestations vary extensively. The brain mechanisms linking this CNV to social behavioral traits relevant to ASD remain poorly understood, but emerging evidence suggests a key role for immune-brain interactions. Despite the availability of mouse models for 16p11.2 deletion, research on social behavior in this CNV and on the underlying neura...

Negr1 upregulation converges into core impaired processes in autism spectrum disorders: from pathophysiology to potential therapeutic target

Autism spectrum disorders (ASDs) are a group of medical conditions encompassing diverse neurodevelopmental syndromes (e.g., Fragile X) caused by alterations in specific genes. Although all ASDs converge into common core behaviors (i.e. social deficits and repetitive behaviors), genetic variants in ASD are very heterogeneous. Nowadays there is no effective treatment for core behavior impairments in autism, and numerous key mechanisms remain unknown, although preliminary insights have been gain...

Contribution of multiple sensory modalities to texture discrimination in head-fixed mice

Decision-making tasks involving the somatosensory system, such as texture discrimination, have been extensively used to investigate the cellular and circuit mechanisms underlying the processing of sensory information in rodents and are believed to rely primarily on whisker-mediated inputs. However, when whiskers are used to explore the environment, a process called “whisking”, mice may combine tactile inputs with those from other sensory modalities (e.g., olfaction and vision). In fact, whisk...

Improving Transparency, Trust, and Automation in the Software Supply Chain

Modern software no longer functions as a single, monolithic entity but rather as an intricate composition of thousands of components. These components collectively contribute to the functionality and security of software, yet they also expose the ecosystem to an ever-growing array of vulnerabilities. High-profile incidents such as SolarWinds and the 2024 compromise of xz-util highlight the pervasive and severe nature of threats in the software supply chain. These attacks are often opaque, mak...

A Reinforcement Learning Framework for Real-Time Multi-Agent Manipulation Control of Collaborative Robots

The increasing demand for robots across various industries has led to the development of sophisticated robotic systems requiring precise and efficient control. However, achieving true autonomy in dynamic environments remains a significant challenge. This thesis presents a comprehensive framework that bridges the gap between human expertise and robotic autonomy, enabling efficient and safe robot control, particularly in custom production environments. By leveraging deep learning and robotics, ...

Multi-scale Molecular Modeling and Simulations of Voltage-Gated Sodium Channels and their Modulation by the Proline-Rich Transmembrane Protein 2 (PRRT2)

Voltage-gated sodium (NaV) channels control neurons intrinsic excitability by a precise spatiotemporal regulation of ion fluxes through the plasmalemma. They trigger the initiation and propagation of action potentials, key events for the establishment of electrical signaling pathways that span both the central (CNS) and peripheral nervous systems. The experimental determination of NaV channels three dimensional structures has provided insights into the specific conformations associated with ...

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Istituto
  • Università degli Studi di Genova2801
Data di pubblicazione
  • 2020 - 20251703
  • 2010 - 2019840
  • 2008 - 2009258
Settore disciplinare
  • Settore ING-INF/06 - Bioingegneri...202
  • Settore INF/01 - Informatica130
  • Settore BIO/09 - Fisiologia104
  • Settore ING-INF/05 - Sistemi di E...71
  • Settore FIS/07 - Fisica Applicata...54
  • Settore ING-INF/01 - Elettronica52
  • Settore ING-INF/04 - Automatica51
  • Settore MED/38 - Pediatria Genera...51
  • Settore ING-IND/22 - Scienza e Te...49
  • Settore ING-INF/03 - Telecomunica...49
Accesso al fulltext
  • open2153
  • internalNetwork414
  • reserved135
  • embargoed82
  • no fulltext9
  • mixed6
  • partially open2