In the last two decades solid-state nanopores have been widely investigated for the development of efficient and functional sensing platforms that enable real-time identification of biomolecules and even sequencing. Besides the typical electrical readout, single solid-state nanopores have been integrated with plasmonic nanostructures to add additional sensing modalities by using optical techniques such as Surface-enhanced Raman Spectroscopy (SERS). However, these nanosensors often exhibit low throughput which limits their use for real biological applications. Here, a large area and low-cost approach to produce transferrable arrays of plasmonic nanopores is presented. The devices are characterized by optical measurements and tested for the detection of biomolecules by using SERS.
Fabrication and characterization of plasmonic nanopores for Raman detection of biomolecules
IAROSSI, MARZIA
2021
Abstract
In the last two decades solid-state nanopores have been widely investigated for the development of efficient and functional sensing platforms that enable real-time identification of biomolecules and even sequencing. Besides the typical electrical readout, single solid-state nanopores have been integrated with plasmonic nanostructures to add additional sensing modalities by using optical techniques such as Surface-enhanced Raman Spectroscopy (SERS). However, these nanosensors often exhibit low throughput which limits their use for real biological applications. Here, a large area and low-cost approach to produce transferrable arrays of plasmonic nanopores is presented. The devices are characterized by optical measurements and tested for the detection of biomolecules by using SERS.File | Dimensione | Formato | |
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https://hdl.handle.net/20.500.14242/69417
URN:NBN:IT:UNIGE-69417