White matter injury and neuroinflammation in the developing brain: implication of adenosine pathway in clinical and pre-clinical studies

Adenosine blood levels and complications of prematurity in a selected population of very low birth weight infants. We have recently reported high blood adenosine levels in extremely premature infants, positively correlating to their prematurity in function of the body weight classes. Acting via purinergic receptors, adenosine can affect different vulnerable organs including the developing brain.