STEREOSELECTIVE SYNTHESIS OF A-AMINO ACIDS B-SUBSTITUTED WITH A 4,5-DIHYDROISOXAZOLE NUCLEUS AND OF TERTIARY AND QUATERNARY ALLYLSILANES

In the section A of the thesis is presented a stereoselective synthesis of b-hydroxy-a -amino acids b-substituted with a 4,5 dihydroisoxazole nucleus through an aldol type reaction between Schollkopf reagent and isoxazolynil aldehydes and ketones. In the section B is presented the preparation of allyl- or crotylsilane in high dr and er via the lithiation-borylation reaction of alkylcarbamates with silaboronates.The synthesis of quaternary allylsilane through a related strategy is also presented.