Human Exo1 is required to activate the checkpoint response after UV irradiation in human cells. hExo col-localizes with NER factors at the sites of UV lesions and hEXO1 down-regulation by siRNA technology affects DNA repair synthesis.
Human exonuclease 1 connects the ner response and the checkpoint activation after UV induced DNA damage
SERTIC, SARAH
2010
Abstract
Human Exo1 is required to activate the checkpoint response after UV irradiation in human cells. hExo col-localizes with NER factors at the sites of UV lesions and hEXO1 down-regulation by siRNA technology affects DNA repair synthesis.File in questo prodotto:
Non ci sono file associati a questo prodotto.
I documenti in UNITESI sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
Utilizza questo identificativo per citare o creare un link a questo documento:
https://hdl.handle.net/20.500.14242/83525
Il codice NBN di questa tesi è
URN:NBN:IT:UNIMI-83525