UNITesi

Università degli Studi di Genova: [2681] Istituto

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Prodotti della tipologia (ordinati per Data di deposito in Decrescente ordine): 441 a 460 di 2.681
Istituto Anno di pubblicazione Titolo Autore file(s)
Università degli Studi di Genova 2020 Evaluation of the effects of natural and synthetic compounds on lipid accumulation and inflammation in hepatocytes, endotheliocytes and adipocytes. -
Università degli Studi di Genova 2024 Creation Remains. Archivi Digitali, Arti Performative, Processi Creativi -
Università degli Studi di Genova 2021 Innovative techniques for the extraction and quantification of bioactive compounds from food and agroindustrial by-products -
Università degli Studi di Genova 2024 A Security Service for Performance-Aware End-to-End Protection of Sensitive Data in Cloud Native Applications -
Università degli Studi di Genova 2020 L'apprendistato letterario di Raffaele La Capria -
Università degli Studi di Genova 2024 Manifold Learning and Sparsity Priors for Inverse Problems -
Università degli Studi di Genova 2021 The issue of stereochemical control in multicomponent reactions and glycosylation processes. -
Università degli Studi di Genova 2024 La otra orilla. La letteratura di viaggio di Eva Canel ed Emilia Serrano -
Università degli Studi di Genova 2021 I frammenti del grammatico Pio. Edizione, traduzione e commento -
Università degli Studi di Genova 2024 I poteri istruttori del giudice del lavoro -
Università degli Studi di Genova 2022 NETosis Dysregulation in Adenosine Deaminase 2 deficiency (DADA2) -
Università degli Studi di Genova 2024 A Framework for User Representation in Virtual Reality: From Hand Interaction to Full Body Embodiment -
Università degli Studi di Genova 2021 ＜script＞alert('Expect the Unexpected')＜/script＞: Raising Cybersecurity Awareness by Hook or by Crook -
Università degli Studi di Genova 2021 Computational approaches guiding for the design and optimization of novel chemo-types endowed with F508del-CFTR modulator ability -
Università degli Studi di Genova 2024 “We lost our time walking, we must run to get it back". Confini temporali e resistenze nello spazio-tempo EUropeo -
Università degli Studi di Genova 2021 Exceptuando.Teorías sobre la derrotabilidad en la teoría del derecho -
Università degli Studi di Genova 2024 De la lecture à l’écriture : la bibliothèque politique de Jean Giono dans l’œuvre romanesque (1945-1970). Engagement ou désengagement ? -
Università degli Studi di Genova 2020 Targeting Tight Junctions in Nanomedicine: a Molecular Modeling Perspective -
Università degli Studi di Genova 2024 Biomechanics at the multiscale: From tissues to subcellular compartments -
Università degli Studi di Genova 2023 Foul-control paints behavior near anodes of Impressed Current Cathodic Protection systems -
Prodotti della tipologia (ordinati per Data di deposito in Decrescente ordine): 441 a 460 di 2.681
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Prodotti recenti

Du basque au francoprovençal : valorisation des langues régionales ou minoritaires par la conception d'un musée numérique européen

Dalla fine del XXesimo secolo, le lingue moderne non sono più state viste solo come strumenti di comunicazione, ma come un patrimonio culturale immateriale da proteggere. La consapevolezza dell’esistenza di lingue in pericolo di estinzione ha reso urgente la loro salvaguardia. A tal fine, il 5 novembre 1992, il Consiglio d'Europa ha promulgato la Carta europea delle lingue regionali o minoritarie, identificandole come “espressione di ricchezza culturale” e incoraggiando gli Stati membri a pr...

Macrophages and Natural Killer cells in the tumor microenvironment: towards novel immunotherapeutic approaches for neuroblastoma patients

Cancer represents one of the main causes of death in both adults and children. Immunotherapy has significantly advanced cancer treatment, improving survival rates and quality of life for a considerable proportion of patients. However, continued research is essential to enhance outcomes for those who remain resistant to current therapies. The tumor microenvironment (TME) plays a pivotal role in disease progression, driving malignant cell growth and contributing to treatment resistance. In neu...

Phenotypic and functional analysis of human Natural Killer lymphocytes in patients affected by haematological neoplasms treated with autologous T lymphocytes genetically modified with chimeric antigen-specific receptor

Chimeric antigen receptor T cell therapy represents a novel perspective for patients with aggressive, chemotherapy-refractory B cell neoplasms. While CAR-T cells exhibit direct cytotoxic properties, other immune populations may also contribute to treatment response and complications. Macrophages and dendritic cells are recognized as key-mediators of CAR-T cell associated inflammatory toxicities, while emerging evidence suggests that regulatory T cells may hamper CAR-T cell efficacy. To invest...

Naturally-Derived, Bioactive, Zein Microparticles for Wound Healing: Efficiency Optimization via Spray Drying

Wound healing is a delicate process comprising various phases, of which inflammation constitutes the most critical one. Some wounds fail to evolve from this state due to pre-existing pathologies or medical conditions, such as diabetes, becoming chronic and causing pain and serious consequences for the patients. Wounds are defined chronic when they fail to heal in a time span that ranges from four weeks to three months and, as an extreme consequence, can eventually lead to gangrene and patient...

Photovoltaic solar energy conversion: prediction models applied to tracking and fixed-tilt systems at European scale

The present Ph.D. thesis aims to present the development of models for diagnostic of large photovoltaic plants, the maximization of the solar radiation captured by ground-mounted bifacial plants, both fixed and single-axis tracking, and the optimization of the exploitation of the solar resource in urban-integrated systems. The first part of the work concerns the development of robust models for predicting the performance and enabling automated monitoring of large-scale photovoltaic systems,...

Investigating the Role of Immune Response Markers in Predicting Severity and Prognosis in COVID-19 Patients: A Retrospective Study from the ASL1 Emergency Department

This retrospective observational study aimed to explore the relationship between immune markers and COVID-19 severity in patients admitted to the emergency department of ALS1 in the Liguria region. By examining the correlation between various immune markers and disease progression, the study seeks to enhance our understanding of how immune responses influence the severity of COVID-19 in this specific patient cohort. We evaluated T-cell reactivity (Coviferon test), IgM and IgG anti...

Analysis of clinical presentations, adaptive and innate immune correlates of Vaccine-associated Post-Acute SARS-Coronavirus Syndrome (PASC-vac)

Post-vaccination acute sequelae of SARS-CoV-2 (PASC-vac) is a condition characterized by persistent neurological and immunological symptoms following COVID-19 vaccination. This study explores the clinical manifestations, immune correlates, and potential pathogenic mechanisms underlying PASC-vac. A cohort of 71 PASC-vac patients and 19 healthy donors was analyzed through immunological assessments, including flow cytometry, serum antibody profiling, and tissue examination. The findings indicate...

Rational design of multi-compartmentalized µMESH implants for the treatment of brain disorders

Despite advances in targeted therapies, the survival rate for glioblastoma (GBM) patients has not improved over the past 20 years. The efficacy of GBM treatment remains constrained by non-specific distribution, tumor heterogeneity, and a highly immunosuppressive microenvironment. An innovative drug delivery system – µMESH – has recently been developed to address these challenges. This platform consists of a flexible, biodegradable, dual-compartment polymeric film, and previous results have de...

Tissue-resident Natural Killer cells in human lung cancer

Background: Natural killer (NK) cells, part of the innate lymphoid cell family, represent the third major lymphocytic population in the peripheral blood and are traditionally divided into CD56dimCD16+ and CD56brightCD16− subsets. However, recent research has identified tissue-resident(tr) NK cells in different organs, such as lung and liver. These cells are distinguished by the circulating counterpart by expression of markers, such as CD103, CD69, CXCR6, and CD49a responsible for their retent...

Sulfavant A: Dissecting immunomodulatory mechanisms in vitro and in vivo for translational immunotherapy

Sulfavant A (SA), un nuovo adiuvante sulfolipidico sintetico derivato da alghe marine, rappresenta un approccio trasformativo nell’immunomodulazione e nella tecnologia degli adiuvanti. Questo studio esplora le proprietà immunomodulatorie di Sulfavant A, con particolare attenzione ai suoi effetti sulle cellule natural killer (NK). Esaminando la modulazione della risposta immunitaria in funzione della concentrazione e del contesto, attraverso l’espressione dei recettori, l'attivazione e la funz...

Scopri
Istituto
  • Università degli Studi di Genova2681
Data di pubblicazione
  • 2020 - 20251610
  • 2010 - 2019813
  • 2008 - 2009258
Settore disciplinare
  • Settore ING-INF/06 - Bioingegneri...190
  • Settore INF/01 - Informatica120
  • Settore BIO/09 - Fisiologia90
  • Settore ING-INF/05 - Sistemi di E...66
  • Settore FIS/07 - Fisica Applicata...51
  • Settore ING-INF/01 - Elettronica51
  • Settore MED/38 - Pediatria Genera...51
  • Settore ING-IND/22 - Scienza e Te...49
  • Settore ING-INF/03 - Telecomunica...46
  • Settore FIS/03 - Fisica della Mat...45
Accesso al fulltext
  • open2049
  • internalNetwork414
  • reserved135
  • embargoed67
  • no fulltext8
  • mixed6
  • partially open2