Ru(II) Metal Complexes: Synthesis, Interaction with Mitochondrial G-Quadruplex, and Biological Activity

I composti a base di platino restano tra i pilastri della chemioterapia antitumorale, ma la loro efficacia è spesso limitata da elevata tossicità sistemica e dall’insorgenza di fenomeni di farmacoresistenza. Tali limiti rendono urgente lo sviluppo di nuovi metallo-farmaci alternativi. In questo contesto, i complessi di rutenio rappresentano una promettente classe di candidati, come dimostrano due molecole, BOLD-100 e TLD-1433, attualmente in fasi avanzate di sperimentazione clinica per il tra...

CO₂ VALORIZATION: CATALYSTS FOR CH₄ AND CO₂ RECYCLING AND SYSTEMS FOR THE SUSTAINABLE FORMATION OF C–C BONDS

Rising atmospheric CO2 emission, driven by population growth and continued reliance on fossil carbon, poses several climate, energy, and resource challenges. Beyond capture and storage, CO₂ valorization offers a path to close the carbon circle by converting CO2 (often with CH4 or H2) into fuels and chemicals. This thesis addresses that challenge by developing and exploring different catalytic routes that couple activity and selectivity with robustness, using a consistent synthesis-structure-f...

Forecast, Foresight, and Adaptation: An Adaptive Strategy Framework for the Hospitality Industry Integrating Data-Driven Forecasting into Strategic Decision-Making

This dissertation advances a comprehensive framework for understanding how forecasting, foresight, and adaptive learning interact to shape strategic decision-making in the hospitality industry. It proposes the concept of an Adaptive Strategy Framework, in which organizations continuously move through a cyclical process of sensing, interpreting, and responding to change. Within this system, forecasting represents the predictive layer that transforms data into anticipatory insights; foresight s...

Beyond Recognition: Towards Sonic Opacity as Algorithmic Resistance

The doctoral thesis Beyond Recognition: Towards Sonic Opacity as Algorithmic Resistance, presents an intervention at the intersection of critical theory, media studies, sound studies and artistic research that seeks to critically assess recognition as a regime traversing epistemological, ethical, aesthetic and technological domains. In particular, the thesis concentrates on listening as a sensory-specific mode of recognition; on human voice as the overdetermined object of auditory recognition...

Navigating stakeholder complexity: How social media platforms, NGO-company interactions, and stakeholder coordination shape transparency in environmental disclosure.

This doctoral thesis is structured in five chapters. Chapter 1 outlines the different literature streams addressed in this thesis. It presents the literature gaps and research questions, highlights the relevance of the arguments, and describes the research methodologies adopted. Chapter 2 presents the first research stream which is based on the research article by Crapa et al., (2024), “The performance of green communication across social media: Evidence from large-scale retail industry in It...

Learning and Adaptation for Efficient and Resilient Internet of Underwater Things Communications

The advent of the Internet of Underwater Things (IoUT) is reshaping communication and computation in marine environments. Unlike terrestrial wireless systems, where abundant spectrum and cloud resources enable complex processing and centralized optimization, UnderWater Acoustic (UWA) networks must operate under extremely harsh and constrained conditions. The acoustic channel suffers from scarce and frequency-dependent bandwidth, long propagation delays, and high variability caused by multipat...

IL DISTURBO DA ANSIA SOCIALE NELLA SOCIETÀ DELL’INCERTEZZA. ANALISI DEL FENOMENO IN UNA PROSPETTIVA PSICOPEDAGOGICA.

This dissertation examines social anxiety as a complex and situated phenomenon at the intersection of medical anthropology, ethnopsychology, and cultural psychopathology. Its central argument is that Social Anxiety Disorder (SAD) cannot be understood solely as a clinical category; rather, it constitutes a historically produced configuration of vulnerability shaped by regimes of visibility, familial expectations, moral frameworks, and the broader social conditions of late modernity.The thesis ...

Valorizzazione di matrici vegetali e sottoprodotti agroalimentari: indagine fitochimica e studio delle attività biologiche di Boswellia sacra Flueck., frutti di sommacco (Rhus coriaria L.) e semi di lampone rosso (Rubus idaeus L.) per applicazioni orientate allo sviluppo di ingredienti nutraceutici innovativi e sostenibili

Metal-phthalocyanines and Imidazolium Bromide Copolymers: a "lego-like" assembly of bifunctional heterogeneous catalysts for different catalytic applications