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Libera Università Vita-Salute San Raffaele di Milano: [285] Istituto

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Prodotti della tipologia (ordinati per Data di deposito in Decrescente ordine): 201 a 220 di 285
Istituto Anno di pubblicazione Titolo Autore file(s)
Libera Università Vita-Salute San Raffaele di Milano 2023 INTRACELLULAR IRON OVERLOAD AFFECTS HSC METABOLISM BY IMPAIRING MITOCHONDRIAL FITNESS IN β-THALASSEMIA -
Libera Università Vita-Salute San Raffaele di Milano 2023 Th1-LIKE HBV-SPECIFIC CD4+T CELLS ARE ABLE TO REVERT THE CD8+T CELL DYSFUNCTION INDUCED BY HEPATOCELLULAR PRIMING -
Libera Università Vita-Salute San Raffaele di Milano 2022 The visual pathway as a platform to assess demyelination and neurodegeneration in multiple sclerosis: the paradigms of acute optic neuritis and progressive course -
Libera Università Vita-Salute San Raffaele di Milano 2023 Investigation of intratumoral cd8+ t cell spatiotemporal localization and function -
Libera Università Vita-Salute San Raffaele di Milano 2022 Clinical and surgical validation of advanced neuroimaging for enhanced assessment of brain tumors. -
Libera Università Vita-Salute San Raffaele di Milano 2022 Unveiling the biological role of human circulating Hematopoietic Stem and Progenitor cells -
Libera Università Vita-Salute San Raffaele di Milano 2023 STRUCTURAL AND FUNCTIONAL MAGNETIC RESONANCE (MR) GUIDED FUNCTIONAL NEUROSURGERY FOR MOVEMENT DISORDERS -
Libera Università Vita-Salute San Raffaele di Milano 2023 IL DISTURBO DEL LINGUAGGIO PRAGMATICO NELLA SCHIZOFRENIA: VALUTAZIONE E CORRELATI ELETTROFISIOLOGICI -
Libera Università Vita-Salute San Raffaele di Milano 2023 ESPLORAZIONE DELLA FENOMENOLOGIA PLEOMORFICA DELLO SPETTRO DELLA NEUROMIELITE OTTICA CON LA RISONANZA MAGNETICA -
Libera Università Vita-Salute San Raffaele di Milano 2022 AQP11 mediates H2O2 fluxes to regulate cellular redox homeostasis and signalling -
Libera Università Vita-Salute San Raffaele di Milano 2021 Il ritmo come "filo conduttore" della filosofia di Friedrich Nietzsche. Dalle lezioni basileesi di ritmica e metrica antica all'arte del "grande ritmo". -
Libera Università Vita-Salute San Raffaele di Milano 2021 ADVANCED COGNITIVE, MOLECULAR AND STRUCTURAL BIOMARKERS IN PRECLINICAL AND PRODROMAL DEMENTIA PHASES -
Libera Università Vita-Salute San Raffaele di Milano 2023 Identificazione di marcatori imaging per caratterizzare l’aggressività biologica di neoplasie pancreatiche/esofagee e predire l’efficacia di trattamenti neoadiuvanti: un approccio radiomico traslazionale. -
Libera Università Vita-Salute San Raffaele di Milano 2021 Individual neuroanatomical constraints on cognition and language -
Libera Università Vita-Salute San Raffaele di Milano 2022 Multidirectional dysfunction of the immune response in patients with systemic lupus erythematosus -
Libera Università Vita-Salute San Raffaele di Milano 2023 LA NOZIONE DI “CLASSICO”. STORIA DELL’IDEA DI CLASSICITÀ. IL PROBLEMA DELLO STUDIO DELLE MATERIE UMANISTICHE. -
Libera Università Vita-Salute San Raffaele di Milano 2023 Unraveling the physiopathological role of sacsin, the protein mutated in autosomal recessive spastic ataxia of Charlevoix–Saguenay (ARSACS) -
Libera Università Vita-Salute San Raffaele di Milano 2023 Agency in progress: The ethics, evolution, and psychology of moral change -
Libera Università Vita-Salute San Raffaele di Milano 2023 Lss KNOCK-IN MOUSE MODEL OF SALT-SENSITIVE HYPERTENSION AND RENAL GLOMERULAR DAMAGE -
Libera Università Vita-Salute San Raffaele di Milano 2022 TOWARD A NEW MODEL OF BORDERLINE PERSONALITY DISORDER: A PSYCHOPHYSIOLOGICAL APPROACH ON THE LINK BETWEEN EMOTIONAL AND BEHAVIORAL DYSREGULATION -
Prodotti della tipologia (ordinati per Data di deposito in Decrescente ordine): 201 a 220 di 285
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Prodotti recenti

Degenerazione assonale nelle neuropatie periferiche: dai meccanismi molecolari all’approccio terapeutico

La malattia di Charcot-Marie-Tooth (CMT) è la neuropatia periferica ereditaria più frequentemente osservata, con una prevalenza di circa 1 su 2.500 persone. È un gruppo di patologie geneticamente eterogeneo, con mutazioni in oltre 100 geni, che colpisce sia i nervi motori sia quelli sensoriali. La mutazione T124M nel gene MPZ dà origine alla CMT2J, un sottotipo particolarmente interessante con una particolare prevalenza nell’Italia settentrionale. Sebbene MPZ sia una proteina esclusivamente e...

Lo studio dell'età cellulare sulla funzione delle β cellule derivate da iPSC

Una fonte affidabile di β cellule è essenziale per l'avanzamento della terapia cellulare nel diabete di tipo 1. Le cellule staminali pluripotenti indotte possono differenziarsi in β cellule produttrici di insulina, imitando efficacemente lo sviluppo pancreatico in vitro. Mentre la senescenza cellulare supporta la formazione di β cellule durante l'embriogenesi, la loro senescenza cellulare legata all'invecchiamento compromette il rilevamento del glucosio e la secrezione di insulina. Tuttavia, ...

Imaging, genetic and biomarkers characterization of arrhythmic mitral valve prolapse

Association between genotype and phenotype in mitral valve prolapse patients and their impact on arrhythmic outcomes

Digital Cognitive Assessment and its Relationship with Disability in Multiple Sclerosis

Introduction. Cognitive impairment is common in people with MS (pwMS) and significantly impacts functional independence. The Symbol-Digit Modalities Test (SDMT) is widely used to assess cognitive deficits in pwMS. Electronic adaptations of the SDMT (eSDMT) can enable remote monitoring and capture more detailed performance metrics, compared to pen-and-paper tests. This study details the development and validation of a custom-made eSDMT intended to enable long-term remote cognitive monitoring o...

At-home extension of computerised cognitive rehabilitation in People with Progressive Multiple Sclerosis: A Feasibility and Efficacy Pilot Randomised Controlled Trial

A great proportion of People with Multiple Sclerosis (PwMS) suffers from Cognitive Impairment (CI), which greatly diminishes the quality of life of those affected. Pharmacological treatments for CI in PwMS showed limited efficacy, and behaviourally-based interventions still remain the preferred care option. These typically involve in-clinic repeated one-on-one sessions with a therapist for a set period of time. This has been seen to be both costly and unfeasible for some PwMS. Telerehabilitat...

FUTURE-MAKER-GENERATIONS. CRITICAL PHENOMENOLOGY AND TRANSGENERATIVE SOCIAL ONTOLOGY

This thesis introduces the concept of Future-Maker Generations (FMGs), a novel form of plural subject described as an ethical and political community, globally disseminated and axiologically oriented towards the defence of plurality of all forms of life. The thesis aims to describe and analyse the emerging of FMGs from Future-Maker Personalities (FMPs), individuals united by a shared set of values oriented towards human plurality, global solidarity, human rights, and environmental protection....

LNA-ASO based therapy for the treatment of SARS-CoV-2 infection in pre-clinicals models

The COVID-19 crisis and the development of the first approved mRNA vaccine have highlighted the potential of RNA-based therapeutic strategies. Mutated variant strains of SARS-CoV-2 that evade immunity to previous infection or vaccination are continuously emerging, resulting in new outbreaks. Thus, there is a clear and urgent need for alternative approaches that are active against multiple variants of concern. Antisense oligonucleotides (ASOs) represent a new and promising class of RNA-targete...

Pregnancy during a pandemic: a deep phenotyping approach exploring the role of inflammation on postpartum cognitive decline and depression.

Peripartum depression (PPD) results in physical, emotional, and behavioral changes during pregnancy and postpartum that occur in roughly 20% of women, yet COVID-19 may have increased the prevalence of PPD. Furthermore, during this period, women may be vulnerable to the development of cognitive deficits. The biological causes of PPD and cognitive decline are still unclear. These issues may arise due to brain structural and functional alterations; however, results are inconclusive. Moreover, dy...

FUNCTIONAL AND STRUCTURAL MRI CORRELATES OF COGNITIVE DYSFUNCTION IN PEDIATRIC MS AND A COMPARISON OF COGNITIVE RESILIENCE WITH ADULT-ONSET MS

During my PhD, I focused on the study of the MRI substrates of cognition in pediatric-onset (PO) multiple sclerosis (MS) patients and on the validation of a novel paper-pencil cognitive test, the Consecutive-letter Substitution Test (CST), to assess information processing speed (IPS). By applying unsupervised machine learning, we identified three cognitive phenotypes in pediatric MS patients: normal functioning, mild verbal memory and semantic fluency deficits, and global impairment, each as...

Trust, Science and Disinformation

In this dissertation, my aim is to analyse the reasons and causes behind the spread of disinformation. In particular, my main interest is in what I will refer to as “scientific disinformation”, namely the kind of disinformation that regards scientific issues and topics, with a particular focus on climate change. The thesis is divided into five chapters, each with a specific purpose. The first chapter is dedicated to the definition of disinformation. I review the different definitions of disin...

Scopri
Istituto
  • Libera Università Vita-Salute San...285
Data di pubblicazione
  • 2020 - 2025200
  • 2010 - 201944
  • 2004 - 200941
Settore disciplinare
  • Settore BIO/11 - Biologia Molecolare31
  • Settore MED/26 - Neurologia21
  • Settore BIO/13 - Biologia Applicata20
  • Settore MED/04 - Patologia Generale20
  • Settore M-PSI/02 - Psicobiologia ...8
  • Settore MED/25 - Psichiatria7
  • Settore M-FIL/01 - Filosofia Teor...5
  • Settore M-FIL/03 - Filosofia Morale4
  • Settore M-FIL/05 - Filosofia e Te...4
  • Settore MED/15 - Malattie del Sangue4
Accesso al fulltext
  • open158
  • internalNetwork68
  • embargoed36
  • no fulltext10
  • mixed7
  • reserved6