LA RICERCA SISTEMATICA DEI TUMORI PROFESSIONALI: ATTIVAZIONE E PRIMI RISULTATI DEL REGISTRO TUMORI DEI SENI NASALI E PARANASALI DELLA LOMBARDIA

We present the findings of the first years of activity of the Lombardy registry of sinonasal cancers (SNC), which was started at the end of 2007. The registry collects all potential cases of primary malignant epithelial neoplasm of the nasal cavity and accessory sinuses, verifies clinical records, and interviews the patients or their next-of-kin to investigate exposures to known SNC carcinogens. Case ascertainment is complete for the year 2008: we recorded 31 verified cases among men and 24 among women. The age-standardized regional incidence rates were 0.8 and 0.5  100,000 in men and women, respectively. For 87 cases diagnosed in 2008-2010 period we obtained an interview. In 34 cases (32 M and 2 F), we documented occupational exposure to wood dust (61.8%), leather dust (29.4%), bitumen fumes (5.9%), and hexavalent chromium compounds (2.9%). For these subjects compensation claims were undertaken. In 4 cases we found leisure-time exposures. In 49 cases (56.3%) no evidence of exposure to known SNC carcinogens was found.