Libera Università Vita-Salute San Raffaele di Milano

Libera Università Vita-Salute San Raffaele di Milano: [661] Istituto

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Prodotti della tipologia (ordinati per Data di deposito in Decrescente ordine): 81 a 100 di 661

Loss and replacement of ceruloplasmin ferroxidase activity in neurodegeneration

2016

Monocytes are required for antileukemia efficacy and toxicities by CAR-T cells

2016

Il percorso storico delle idee di embrione, feto e aborto nel mondo antico e medievale

2016

Retargeting T cells against leukemia by lipid-specific TCR

2016

New insights into glaucoma diagnosis, medical and surgical treatment

2016

Biomaterial and cell-based approaches to promote regeneration after spinal cord injury

2016

Pathophysiological meaning of the paramagnetic rim in multiple sclerosis lesions a 7T MRI-pathology study

2016

Patient-specific induced pluripotent stem cells (iPSC) for ex vivo gene therapy and modelling of metachromatic leukodystrophy

2016

Smithian prudence and its relevance in moral philosophy and neuroscience

2016

La resistenza della materia studio sul rapporto tra corporeità e senso nell'antropologia filosofica di Helmuth Plessner

2016

Development of new strategies for improving microglia reconstitution after hematopoietic stem cell transplantation

2016

Harnessing the therapeutic improvements of genetically engineered neural stem cell in a preclinical model of multiple sclerosis

2016

Improving the safety of lentiviral vector integration with chromatin insulators

2016

Ontologia della trasfigurazione contributo allo studio della storia della filosofia russa

2016

Quatenus fit logica del sentire e logica del pensare in Antonio Rosmini e Giovanni Gentile

2016

HMGB1 and nucleosome number modulation in the transcriptional response to stress

2015

Role of the ERAD pathway in the physiology and disease of peripheral nerves myelination

2015

Genetics of premature ovarian failure and early menopause

2012

Anti-apoptotic effects of interleukin 7 in human immunodeficiency virus type 1 infection mechanism and implications for immune reconstitution strategies

2011

Interaction with CD1d-expressing APCs regulate iNKT cell functions by tuning SHP-1 expression

2011

Istituto	Anno di pubblicazione	Titolo	Autore
Libera Università Vita-Salute San Raffaele di Milano	2016	Loss and replacement of ceruloplasmin ferroxidase activity in neurodegeneration	-
Libera Università Vita-Salute San Raffaele di Milano	2016	Monocytes are required for antileukemia efficacy and toxicities by CAR-T cells	-
Libera Università Vita-Salute San Raffaele di Milano	2016	Il percorso storico delle idee di embrione, feto e aborto nel mondo antico e medievale	-
Libera Università Vita-Salute San Raffaele di Milano	2016	Retargeting T cells against leukemia by lipid-specific TCR	-
Libera Università Vita-Salute San Raffaele di Milano	2016	New insights into glaucoma diagnosis, medical and surgical treatment	-
Libera Università Vita-Salute San Raffaele di Milano	2016	Biomaterial and cell-based approaches to promote regeneration after spinal cord injury	-
Libera Università Vita-Salute San Raffaele di Milano	2016	Pathophysiological meaning of the paramagnetic rim in multiple sclerosis lesions a 7T MRI-pathology study	-
Libera Università Vita-Salute San Raffaele di Milano	2016	Patient-specific induced pluripotent stem cells (iPSC) for ex vivo gene therapy and modelling of metachromatic leukodystrophy	-
Libera Università Vita-Salute San Raffaele di Milano	2016	Smithian prudence and its relevance in moral philosophy and neuroscience	-
Libera Università Vita-Salute San Raffaele di Milano	2016	La resistenza della materia studio sul rapporto tra corporeità e senso nell'antropologia filosofica di Helmuth Plessner	-
Libera Università Vita-Salute San Raffaele di Milano	2016	Development of new strategies for improving microglia reconstitution after hematopoietic stem cell transplantation	-
Libera Università Vita-Salute San Raffaele di Milano	2016	Harnessing the therapeutic improvements of genetically engineered neural stem cell in a preclinical model of multiple sclerosis	-
Libera Università Vita-Salute San Raffaele di Milano	2016	Improving the safety of lentiviral vector integration with chromatin insulators	-
Libera Università Vita-Salute San Raffaele di Milano	2016	Ontologia della trasfigurazione contributo allo studio della storia della filosofia russa	-
Libera Università Vita-Salute San Raffaele di Milano	2016	Quatenus fit logica del sentire e logica del pensare in Antonio Rosmini e Giovanni Gentile	-
Libera Università Vita-Salute San Raffaele di Milano	2015	HMGB1 and nucleosome number modulation in the transcriptional response to stress	-
Libera Università Vita-Salute San Raffaele di Milano	2015	Role of the ERAD pathway in the physiology and disease of peripheral nerves myelination	-
Libera Università Vita-Salute San Raffaele di Milano	2012	Genetics of premature ovarian failure and early menopause	-
Libera Università Vita-Salute San Raffaele di Milano	2011	Anti-apoptotic effects of interleukin 7 in human immunodeficiency virus type 1 infection mechanism and implications for immune reconstitution strategies	-
Libera Università Vita-Salute San Raffaele di Milano	2011	Interaction with CD1d-expressing APCs regulate iNKT cell functions by tuning SHP-1 expression	-

Prodotti della tipologia (ordinati per Data di deposito in Decrescente ordine): 81 a 100 di 661

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Prodotti recenti

Studying immunometabolic alterations in age-related diseases

The tricarboxylic acid (TCA) cycle is a core metabolic pathway for the generation of mitochondrial ATP and key anabolic intermediates in cells. Succinate dehydrogenase (SDH), the enzymatic complex that catalyzes the oxidation of succinate to fumarate in the TCA cycle, stands as the first mitochondrial enzyme found mutated in cancer. Loss of SDH function disrupts the TCA cycle and triggers succinate accumulation in tumor cells. However, how tumors cope with a dysfunctional TCA cycle remains la...

VALIDATION OF ARTIFICIAL EPIGENETIC SILENCER TO REDUCE GLIOBLASTOMA IN IMMUNOCOMPETENT MOUSE MODEL

Glioblastoma (GBM) is the most aggressive primary brain tumor in adults and remains associated with extremely poor prognosis despite multimodal treatment, including surgery, radiotherapy, and chemotherapy. The limited efficacy of current therapies reflects key features of this malignancy, including marked inter- and intra-tumoral heterogeneity, highly infiltrative growth, and the strong influence of the tumor microenvironment on disease progression and therapeutic response. In particular, the...

Una piattaforma universale per l'aggiunta mirata e senza soluzione di continuità di geni mediante selezione saturante auto-rinforzante nelle cellule staminali ematopoietiche umane

Terapia genica tramite editing con HDR su cellule staminali emopoietiche

Svelare l’impatto del microbiota sulla fibrosi intestinale: nuove prospettive per la patogenesi e il trattamento delle complicanze associate al morbo di Crohn.

Complicanze fibrotiche della malattia di Crohn

Lo standard setting delle organizzazioni internazionali per la Pubblica Amministrazione nell'epoca della fine dell'ordine globale neoliberale

La tesi analizza l'impatto dello standard setting delle organizzazioni internazionali (in particolare delle Nazioni Unite) per la pubblica amministrazione nell'attuale scenario di fine dell'ordine globale neoliberale.

REFORMING COMMUNICATION IN PUBLIC ADMINISTRATION: A RESEARCH ON INCLUSIVE LANGUAGE

Linguaggio inclusivo di genere

Proliferative stress and DNA damage response pathways in hematopoietic stem cell gene therapy and clonal hematopoiesis

Gene editing (GE) of hematopoietic stem and progenitor cells (HSPCs) holds significant therapeutic promise but remains constrained by genotoxic risks associated with DNA double-strand breaks, donor template delivery, and proliferation-induced stress during ex vivo manipulation. Ex vivo culture is indispensable to achieve efficient homology-directed repair (HDR), yet comes at the cost of inducing cellular stress and compromising HSPC fitness. Here, we identify p38 MAPK signaling as a central r...

Studying human Hematopoietic Stem/Progenitor Cells Trafficking in vivo

Hematopoiesis, Gene Therapy

Unraveling the role of the alarmin HMGB1 in the ageing process

High Mobility Group Box 1 (HMGB1) is a nuclear protein that, in physiological conditions, is predominantly localized in the nucleus. Upon cellular stress, it can translocate to the cytosol and can be released extracellularly, where it regulates tissue regeneration and inflammatory responses in a redox-state-dependent manner. HMGB1 bioactivities has been associated with several hallmarks of aging, and HMGB1 has been recently proposed as a biomarker of frailty. Here we hypothesized that aging p...

Unravelling the role of Integrated Stress Response signalling in metastatic Breast Cancer bioenergetics

The Integrated Stress Response (ISR) is an evolutionarily conserved adaptive pathway that mediates translation reprogramming in response to microenvironmental stress, often hijacked by cancer cells to promote metastasis. To reveal novel targetable vulnerabilities in Triple-negative Breast Cancer (TNBC), the most aggressive breast cancer subtype, characterized by high metastatic propensity and limited therapeutic options, here we elucidate the mechanisms by which ISR accommodates the energy de...

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