UNITesi

Università degli Studi di Milano: [10112] Istituto

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Prodotti della tipologia (ordinati per Data di deposito in Decrescente ordine): 81 a 100 di 10.112
Istituto Anno di pubblicazione Titolo Autore file(s)
Università degli Studi di Milano 2026 RARE BLEEDING DISORDERS: INSIGHTS INTO CLINICAL PRESENTATION, LABORATORY PHENOTYPE, AND GENETIC CHARACTERIZATION -
Università degli Studi di Milano 2026 HIGH-THROUGHPUT PROFILING OF INNATE IMMUNE CELLS TO UNVEIL TUMOR ESCAPE MECHANISMS IN MATCHED COLORECTAL CANCER AND LIVER METASTASES -
Università degli Studi di Milano 2026 LE ETIMOLOGIE GRECHE NEI COMMENTARII DI SERVIO A VIRGILIO -
Università degli Studi di Milano 2026 THERANOSTIC PLATINUM-BASED COMPLEXES FOR GLIOBLASTOMA TREATMENT AND EVALUATION OF THEIR LOADING AND RELEASE FOR DRUG DELIVERY -
Università degli Studi di Milano 2026 SYNTHESIS, CHARACTERIZATION AND EVALUATION OF BIOACTIVE MOLECULES LINKED TO PHOTOREMOVABLE PROTECTING GROUPS FOR SPATIO-TEMPORAL CONTROL OF THEIR ACTIVITY THROUGH PHOTOACTIVATION -
Università degli Studi di Milano 2026 DISSECTING IMMUNE DYSREGULATION IN PATIENTS WITHTHYMIC EPITHELIAL TUMORS BY AUTOANTIBODY ANDSINGLE-CELL PROFILING -
Università degli Studi di Milano 2026 EFFECTS OF NIGHT SHIFT WORK ON REPRODUCTIVE HEALTHIN A POPULATION OF HEALTHCARE WORKERS -
Università degli Studi di Milano 2026 DISSECTING THE ROLE OF THE TETRASPANIN MS4A4A IN MODULATING MACROPHAGE PLASTICITY AND FUNCTION -
Università degli Studi di Milano 2026 CONTINUOUS-FLOW STRATEGIES FOR THE PREPARATION OF ACTIVE PHARMACEUTICAL INGREDIENTS AND RELEVANT INTERMEDIATES -
Università degli Studi di Milano 2026 EXPLORING UNPRECEDENT SYNTHETIC ROUTES FOR CHIRAL AMINO DERIVATIVES -
Università degli Studi di Milano 2026 DUAL TARGETING OF RFAP AND FIMH IMPAIRS AIEC INTRACELLULAR SURVIVAL AND LIMITS OMV-DEPENDENT IL-23/PTH17 AXIS ACTIVATION, OFFERING A NOVEL THERAPEUTIC STRATEGY FOR CROHN¿S DISEASE -
Università degli Studi di Milano 2026 NOVEL THERAPEUTIC APPROACHES EMERGING FROM HCN CHANNELS STRUCTURAL AND FUNCTIONAL STUDIES -
Università degli Studi di Milano 2026 DESIGN, DEVELOPMENT AND VALIDATION OF NOVEL ELECTRICAL CONTACTING SYSTEMS, MECHANICAL ENCAPSULATION SOLUTIONS AND HIGH-RESOLUTION INTEGRATED CHARGE-SENSITIVE PREAMPLIFIERS FOR ADVANCED HIGH-PURITY GERMANIUM DETECTORS -
Università degli Studi di Milano 2026 PER UN'ESTETICA NELL'OPERA DI PAUL RICŒUR. UNA TEORIA DEL LINGUAGGIO PERFORMATIVO. -
Università degli Studi di Milano 2026 L¿ 'AMNISTIA' IN ETÀ CLASSICA ED ELLENISTICA. STRATEGIE DI RICONCILIAZIONE E RIDEFINIZIONE DELLA CITTADINANZA A SEGUITO DI CONFLITTI INTERNI -
Università degli Studi di Milano 2026 YEAST DERIVATIVES FOR PRECISION OENOLOGY: EMERGING AND SUSTAINABLE APPLICATION FOR WINE PRODUCTION (WINNY) -
Università degli Studi di Milano 2026 PHARMACOGENOMICS OF OPIOID RESPONSE IN EUROPEAN ADVANCED CANCER PATIENTS -
Università degli Studi di Milano 2026 ULTRA-LOW LEVEL SOLUBLE P24 IS ASSOCIATED WITH INFLAMMATION IN PEOPLE WITH HIV ON LONG-TERM VIROLOGICALLY SUPPRESSIVE ANTIRETROVIRAL THERAPY -
Università degli Studi di Milano 2026 SOCIAL AND REPUTATIONAL DRIVERS OF SUNK-COST SENSITIVITY IN INDIVIDUAL AND COLLECTIVE DECISION-MAKING -
Università degli Studi di Milano 2026 EFFECTS OF DAPAGLIFLOZIN ON EXERCISE CAPACITY, RESPIRATORY FUNCTION, BIOMARKERS, SLEEP APNEA, AND LEFT VENTRICULAR REMODELING IN PATIENTS WITH HEART FAILURE: A PROSPECTIVE, SINGLE CENTER, NON RANDOMIZED STUDY -
Prodotti della tipologia (ordinati per Data di deposito in Decrescente ordine): 81 a 100 di 10.112
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Prodotti recenti

REPROGRAMMING PROLIFERATION: MOLECULAR STRATEGIES AGAINST GLIOBLASTOMA & BACTERIAL PERSISTENCE

Glioblastoma and bacterial persistence, though biologically distinct, pose a shared clinical challenge due to their resilience against pharmaceutical intervention. Part One of this work aims to address limitations in the treatment of glioblastoma, which currently consists of tumour removal and placement of a solid chemotherapy into the resection cavity. This treatment is undoubtedly flawed due to insufficient surface coverage and the high rate of relapse that follows. Our work aims to develop...

SEMICLASSICAL VIBRATIONAL SPECTROSCOPY BEYOND POWER SPECTRA

Infrared (IR) spectroscopy is a fundamental technique for probing molecular structure, dynamics, and intermolecular interactions. However, the increasing spectral complexity of medium- and large-sized systems makes theoretical support essential for reliable spectral assignment. Semiclassical (SC) molecular dynamics offers an effective compromise between accuracy and computational cost, incorporating key quantum effects through the propagation of classical trajectories. Traditionally, SC vibra...

FOOD AND FEED SAFETY IN THE CIRCULAR ECONOMY

This thesis addresses the valorization of agri food co/by-products and former food products (FFPs) for their introduction into animal feed within a circular economy framework. Chapter 1 validated an HPLC-UV method for quantifying theobromine and caffeine, and assessed cocoa hulls (CHs) compliance with EU feed limits, while also characterising polyphenols and antioxidant potential; Chapter 2 profiled FFPs for nutrient composition and methylxanthine levels to estimate methylxanthines exposure ...

SMYD3: A PLAYER IN STEMNESS AND CHROMOSOME INSTABILITY IN TRIPLE NEGATIVE BREAST CANCER

La metilasi delle lisine SMYD3 risulta essere over espressa in diversi tipi di tumore, e legata alla transizione epitelio-mesenchimale (EMT) (1). Inoltre, le cellule staminali del cancro (CSCs) sono cellule iniziatrici del tumore importanti nella formazione di metastasi e correlate all’EMT (2). Il nostro obiettivo era dunque quello di studiare la possibile relazione tra le CSCs e SMYD3 nel cancro al seno triplo negativo (TNBC). I dati prodotti mostrano l’impatto del knock-out (KO) di SMYD3 ne...

INNOVATIVE APPROACHES TO PLANT PROTECTION AND PRODUCE SAFETY THROUGH HIGH-PRECISION PLANT MANAGEMENT SYSTEMS

In recent years, the growing need to minimize the environmental impact of agriculture has encouraged the development of sustainable crop protection strategies that combine biological efficacy, food safety, and the preservation of microbial biodiversity. Within this framework, the use of biocontrol agents (BCAs), ultraviolet (UV) radiation, and advanced diagnostic technologies have emerged as an innovative toolkit for integrated pest management, reducing reliance on conventional agrochemicals....

PVD COATING TREATMENT TOWARDS A SUSTAINABLE AND ECO-FRIENDLY MANUFACTURING SYSTEM

Modern industries face critical challenges of wear, corrosion, and short component lifetimes, all of which impose high environmental and economic costs. Sustainable coating solutions are therefore required to enhance durability while reducing waste and energy consumption. Physical Vapor Deposition (PVD) offers an eco-friendly approach, and in recent years high entropy alloys (HEAs) have emerged as promising candidates for protective coatings due to their exceptional mechanical and corrosion-r...

DEVELOPMENT OF NOVEL BIOTECHNOLOGICAL APPROACHES FOR ACCELERATING GENETIC GAIN IN THE BOVINE

Modern livestock production is increasingly challenged to improve reproductive efficiency while maintaining sustainability and animal welfare standards. Accelerating genetic gain in cattle (Bos taurus) is essential for breeding animals that are more resilient to climate change, more resistant to disease, and capable of higher meat and milk productivity—all while minimizing their environmental footprint. One possible strategy to achieve this goal is to significantly shorten the generati...

INVESTIGATION OF RESILIENCE AND ITS GENETICSTHROUGH THE USE OF LONGITUDINAL DATA

This thesis investigates resilience in dairy cattle using an integrated approach that combines phenotypic characterization, simulation of perturbations, and genomic analysis. The research was motivated by the need to breed animals capable of maintaining productivity amid the environmental and economic challenges facing modern agriculture. Thanks to close collaboration with a medium-large dairy farm in Northern Italy, we had access to a comprehensive dataset of daily milk records and genotype ...

VIRAL SAFETY EVALUATION OF BIOTECHNOLOGY PRODUCTS: DEVELOPMENT AND OPTIMIZATIONOF RELIABLE VIRAL CLEARANCE STRATEGIES

This manuscript brings together the research activities carried out throughout my doctoral program and reflects the dual nature of the project, which developed at the interface between academic research and industrial application. The thesis is part of a broader framework dedicated to the study, optimization, and validation of viral clearance strategies within downstream processing for monoclonal antibody (mAb) production, with the overarching goal of establishing procedures that are effe...

ADVANCES IN MEAN-FIELD OPTIMAL CONTROL VIA DYNAMIC PROGRAMMING EQUATIONS

In questa tesi di dottorato ci proponiamo di analizzare varie classi di problemi di controllo ottimo di tipo McKean-Vlasov con un approccio analitico, che consiste nella caratterizzazione della funzione valore di ciascun problema mediante un'opportuna equazione alle derivate parziali, detta equazione di Hamilton-Jacobi-Bellman (HJB). Poiché i coefficienti di un'equazione stocastica di McKean-Vlasov dipendono non solo dalle traiettorie della soluzione, ma anche dalla sua legge, l'equazione di ...

Scopri
Istituto
  • Università degli Studi di Milano10004
Data di pubblicazione
  • 2020 - 20262074
  • 2010 - 20193748
  • 2000 - 20092371
  • 1990 - 19991642
  • 1986 - 1989138
Settore disciplinare
  • Settore BIO/11 - Biologia Molecolare384
  • Settore BIO/10 - Biochimica340
  • Settore BIO/14 - Farmacologia334
  • Settore MED/04 - Patologia Generale322
  • Settore INF/01 - Informatica223
  • Settore CHIM/06 - Chimica Organica211
  • Settore BIO/09 - Fisiologia165
  • Settore BIO/13 - Biologia Applicata145
  • Settore FIS/03 - Fisica della Mat...126
  • Settore BIO/18 - Genetica120
Accesso al fulltext
  • open5097
  • no fulltext4213
  • embargoed386
  • internalNetwork301
  • partially open7