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Università degli Studi del Piemonte orientale "Amedeo Avogadro": [513] Istituto

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Prodotti della tipologia (ordinati per Data di deposito in Decrescente ordine): 21 a 40 di 513
Istituto Anno di pubblicazione Titolo Autore file(s)
Università degli Studi del Piemonte orientale "Amedeo Avogadro" 2024 Rationally-driven targeting of dihydroorotate dehydrogenase: key enzyme of pyrimidine biosynthesis pathway -
Università degli Studi del Piemonte orientale "Amedeo Avogadro" 2024 Il vuoto e la differenza : decostruzione e vacuità della metafisica -
Università degli Studi del Piemonte orientale "Amedeo Avogadro" 2024 Pre-clinical evaluation of the aldehyde dehydrogenase 1A3 isoform as potential therapeutic target in malignant pleural mesothelioma -
Università degli Studi del Piemonte orientale "Amedeo Avogadro" 2024 Adsorbent materials prepared from natural resources for environmental applications -
Università degli Studi del Piemonte orientale "Amedeo Avogadro" 2024 Evaluation of potential predictive and prognostic biomarkers in patients with advanced lung cancer treated with immunotherapy -
Università degli Studi del Piemonte orientale "Amedeo Avogadro" 2024 XPO1 mutations identify a subgroup of early stage CLL patients characterized by shorter time to first treatment conceivably due to enhanced B cell receptor signaling -
Università degli Studi del Piemonte orientale "Amedeo Avogadro" 2024 The identification of the PYRIN domain as mediator of IFI16-TLR4 interaction reveals a new class of endogenous inflammatory molecules -
Università degli Studi del Piemonte orientale "Amedeo Avogadro" 2025 GWAS era in multiple sclerosis: an integrative approach to explore genotype/phenotype interaction -
Università degli Studi del Piemonte orientale "Amedeo Avogadro" 2024 Microbiota of Vitis vinifera cv. Barbera grapes: a focus on the mycobiota and a look at the culturable indigenous Saccharomyces spp. strains under three different experimental conditions in vineyard -
Università degli Studi del Piemonte orientale "Amedeo Avogadro" 2024 Il Consiglio Superiore della Magistratura e i principi di autonomia e indipendenza : garanzia o minaccia? -
Università degli Studi del Piemonte orientale "Amedeo Avogadro" 2024 Spaces of the Diaspora: urban form and cultural practices of Russian immigrants in Europe and Asia in the first half of the twentieth century -
Università degli Studi del Piemonte orientale "Amedeo Avogadro" 2023 La prossenia in età ellenistica: i decreti ateniesi dalla guerra lamiaca alla conquista romana -
Università degli Studi del Piemonte orientale "Amedeo Avogadro" 2024 Divenire cani: la soggettività canina nella letteratura anglofona vittoriana e modernista -
Università degli Studi del Piemonte orientale "Amedeo Avogadro" 2024 Cell therapy for hemophilia A -
Università degli Studi del Piemonte orientale "Amedeo Avogadro" 2015 Beta human papillomavirus infection and skin cancer in immunocompromised host -
Università degli Studi del Piemonte orientale "Amedeo Avogadro" 2018 Targeted therapies in lung adenocarcinomas: new methodologies and new markers -
Università degli Studi del Piemonte orientale "Amedeo Avogadro" 2014 Expression and distinct functional roles of AKT isoforms in malignant pleural mesothelioma cells -
Università degli Studi del Piemonte orientale "Amedeo Avogadro" 2021 Sex differences in hepatitis C virus infection: characterisation of 17,β-estradiol-modulated antiviral defences in an HCV cell culture system -
Università degli Studi del Piemonte orientale "Amedeo Avogadro" 2016 Studio dei metaboliti del vino da vitigni coltivati in Piemonte attraverso l'uso della spettroscopia NMR -
Università degli Studi del Piemonte orientale "Amedeo Avogadro" 2005 “Impresa e territorio: i fattori territoriali del vantaggio competitivo delle imprese” -
Prodotti della tipologia (ordinati per Data di deposito in Decrescente ordine): 21 a 40 di 513
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Prodotti recenti

From risk to prevention: nutrition and early biomarker discovery in autoimmune diseases

The overarching goal of the Ph.D. project is to investigate the relationship between dietary habits and immune cell perturbations and to find new early disease biomarkers, in the context of MINDFUL (Microvesicles at the Intersection between Autoimmune Diseases, Food, and Unhealthy Lifestyles) project. The exploration of diet as a protective/risk factor for AD started from the development of innovative nutritional epidemiology tools and large database interrogation. Literature reviews undersc...

Reactive oxygen species: a merging solution for two unmerging problems

Malignant mesothelioma is a rare cancer arising from the serosal surfaces of the body, mainly from the pleural layer. The primary cause of pleural mesothelioma is exposure to asbestos fibers, a group of naturally occurring fibrous minerals with excellent physical and electrochemical insulating properties and a long history of industrial applications. Despite a progressive ban on asbestos production and usage in over 50 countries worldwide since the 1980s, the incidence of pleural mesothelioma...

Linear, stellar and hyperbranched copolymers with amphiphilic nature

Amphiphilic copolymers have distinct hydrophobic and hydrophilic segments in their structure. This unique molecular arrangement gives amphiphilic copolymers the ability to self-assemble in suitable solvents to form a variety of nanostructures such as micelles, vesicles or nanoparticles. Solvophobic regions align in a core structure to minimise contact with the solvent, while solvophilic segments interact favourably to form an outer layer that stabilises the nanostructure. The use of controlle...

Sarcopenia: potential new tools to face a giant

Sarcopenia, the age-related decline in muscle mass and functionality associated with poor physical performance, physical disability, and increased mortality, significantly impacts the quality of life in the elderly. While physical exercise is the only effective intervention, it is not always feasible for advanced-stage patients. Thus, the discovery and development of novel approaches to tackle age-related muscle loss are becoming increasingly urgent. Although Vitamin D (VD) deficiency is asso...

A serious game for surgical endoscopy: an innovative virtual reality simulator to democratize endoscopic training

Background: Training on virtual reality simulators (VRS) is effective, shortening the learning curve to competency. However, current simulators are expensive and difficult to access. Low-cost portable VRS could help democratize and standardize endoscopic training. To meet this need, a novel, portable, gamified VRS- Rescue in the Deep (RID)- was developed. Our goal was to assess and validate the efficacy of RID in endoscopic skills assessment. Methods: A randomized comparative trial was perfor...

Discovery and development of small molecules, prodrugs and PROTACs: the role of a modular and reliable chemistry

Drug discovery is an ever-evolving process, driven by the identification of potential disease targets and the emergence of novel technologies and synthetic strategies. In this context, my doctoral research encompasses the development of small molecules (prodrugs and dual targeting inhibitors) and protein degraders (PROTACs) as therapeutic approaches for different diseases, including ultra-rare genetic diseases, autoimmunity, and cancer. To access these compounds, I explored various synthetic...

Biomaterials for bone regeneration possessing novel antibacterial and anti-inflammatory properties: comprehensive biological evaluations

Bone fractures, a common global injury due to trauma, particularly for those with osteoporosis, cause a significant economic burden. Often caused by falls, accidents, or sports, they are frequently treated by healthcare professionals. While the body can heal minor fractures naturally, severe injuries like spinal cord or bone damage might require regenerative surgery. However, this healing ability weakens with age and factors like inflammation from damaged tissue. Implants, widely used in surg...

A phase 3 study of pelebresib plus ruxolitinib for JAK inhibitor-naive patients with myelofibrosis

Background Current treatment strategies in myelofiboris are based on Janus kinase (JAK) inhibitors. Unfortunately, these treatments provide limited depth and durability of response. A potential new treatment paradigm is the combination of novel agents targeting different patways with the current used JAK inhibitors. Herein we present the results of a randomized clinical trial comparing pelabresib, a bromodomain and extraterminal domain (BET) inhibitor, plus ruxolitinib, to placebo plus ruxoli...

Immune system activity in Type 1 Diabetes at the onset: data of MINDFUL project

Background. The onset of type 1 diabetes (T1D) has been associated with altered frequency and phenotype of both innate and adaptive immune cells. Furthermore, an altered frequency or function of extracellular vesicles (EVs) could be implicated in the onset of the disease. EVs are small particles released into biological fluids by all cells and play an important role in intracellular communication. Our primary aim is to characterize the immune system and microvesicles involved in children and ...

Role of lung ultrasonography in critically ill patients

Initially a qualitative diagnostic tool, lung ultrasound (LUS) has transformed into a quantitative method with the development of scoring systems that correlate ultrasound findings with lung density. These systems enhance the ability to grade lung aeration, quantify disease severity, and monitor disease progression and treatment response. This research explored the quantitative aspects of LUS through three projects: 1 Review on Quantitative Techniques: This article reviewed various quantitati...

Scopri
Istituto
  • Università degli Studi del Piemon...513
Data di pubblicazione
  • 2020 - 2025174
  • 2010 - 2019270
  • 2000 - 200968
  • 1997 - 19991
Settore disciplinare
  • Settore MED/04 - Patologia Generale40
  • Settore BIO/10 - Biochimica26
  • Settore BIO/14 - Farmacologia21
  • Settore CHIM/03 - Chimica General...18
  • Settore MED/15 - Malattie del Sangue18
  • Settore BIO/13 - Biologia Applicata13
  • Settore CHIM/06 - Chimica Organica13
  • Settore MED/07 - Microbiologia e ...13
  • Settore CHIM/01 - Chimica Analitica12
  • Settore CHIM/02 - Chimica Fisica11
Accesso al fulltext
  • no fulltext268
  • open161
  • embargoed37
  • internalNetwork35
  • reserved8
  • mixed2
  • partially open2