Università degli Studi del Piemonte orientale "Amedeo Avogadro"

Università degli Studi del Piemonte orientale "Amedeo Avogadro": [686] Istituto

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Prodotti della tipologia (ordinati per Data di deposito in Decrescente ordine): 301 a 320 di 686

Three dimensional oral mucosa models: development and applications

2020

Study of strategies for increasing biocompatibility and effectiveness of polyethylenimine carriers for gene therapy

2015

Tortura, tra abusi e tutela dei diritti fondamentali della persona nel sistema giuridico sovranazionale e nazionale

2020

Teorie e pratiche dello storytelling organizzativo. Applicabilità di modelli di comunicazione narrativa a imprese ed istituzioni: stabilizzazione metodologico-disciplinare e sviluppo operativo

2020

Una visione del mondo meccanicista: Galileo e Mersenne nella filosofia naturale di Thomas Hobbes

2015

Role of Osteopontin/ICOSL/ICOS in multiple sclerosis and cancer

2020

Pentacyclic triterpenic acids as modulators of transcription factors: old scaffolds with a "bright " future?

2019

PCR-based methods for the detection of toxigenic bacteria and filamentous fungi and alternative methods for toxins detection in foods

2017

Prognostic Impact of a 3-MicroRNA Signature on Cytological Samples of Small-Cell Lung Cancer and on Surgical Samples of Squamous Cell Carcinoma of the Lung

2017

In Cell Imaging Techniques to Monitor Glucose Uptake, Cell Migration, and Vesicular Traffic: A Functional Study in Cancer Cells

2016

Role of Diacylglycerol kinase alpha (DGKA) as a therapeutic target in Glioblastoma (GB)

2020

Screening of the SHOX gene in a large cohort of short stature italian patients. Identification of novel likely pathogenic variants through functional characterization

2019

Ecotoxicological profiles of metal engineered nanoparticles in mollusc bivalve Mytilus galloprovincialis

2014

Search for genomic micro-rearrangements through array-CGH in patients with Intellectual Disability and Multiple Pituitary Hormone Deficiency, with standard and custom-design array platforms.

2015

Unacylated ghrelin enhances satellite cell function and relieves the dystrophic phenotype in Duchenne muscular dystrophy mdx model

2017

Hormonal aspects in paediatric obesity

2014

Clinical impact of small TP53 mutated subclones in chronic lymphocytic leukemia

2015

Molecular Determinants of Follicular Lymphoma Transformation to Diffuse Large B cell Lymphoma

2014

Defining the causal association between human beta papillomavirus infection, keratinocyte stem cells expansion and skin cancer development

2017

Role of munc13-4, sap and il-17 in the development of autoimmune lymphoproliferative syndrome

2014

Istituto	Anno di pubblicazione	Titolo	Autore
Università degli Studi del Piemonte orientale "Amedeo Avogadro"	2020	Three dimensional oral mucosa models: development and applications	-
Università degli Studi del Piemonte orientale "Amedeo Avogadro"	2015	Study of strategies for increasing biocompatibility and effectiveness of polyethylenimine carriers for gene therapy	-
Università degli Studi del Piemonte orientale "Amedeo Avogadro"	2020	Tortura, tra abusi e tutela dei diritti fondamentali della persona nel sistema giuridico sovranazionale e nazionale	-
Università degli Studi del Piemonte orientale "Amedeo Avogadro"	2020	Teorie e pratiche dello storytelling organizzativo. Applicabilità di modelli di comunicazione narrativa a imprese ed istituzioni: stabilizzazione metodologico-disciplinare e sviluppo operativo	-
Università degli Studi del Piemonte orientale "Amedeo Avogadro"	2015	Una visione del mondo meccanicista: Galileo e Mersenne nella filosofia naturale di Thomas Hobbes	-
Università degli Studi del Piemonte orientale "Amedeo Avogadro"	2020	Role of Osteopontin/ICOSL/ICOS in multiple sclerosis and cancer	-
Università degli Studi del Piemonte orientale "Amedeo Avogadro"	2019	Pentacyclic triterpenic acids as modulators of transcription factors: old scaffolds with a "bright " future?	-
Università degli Studi del Piemonte orientale "Amedeo Avogadro"	2017	PCR-based methods for the detection of toxigenic bacteria and filamentous fungi and alternative methods for toxins detection in foods	-
Università degli Studi del Piemonte orientale "Amedeo Avogadro"	2017	Prognostic Impact of a 3-MicroRNA Signature on Cytological Samples of Small-Cell Lung Cancer and on Surgical Samples of Squamous Cell Carcinoma of the Lung	-
Università degli Studi del Piemonte orientale "Amedeo Avogadro"	2016	In Cell Imaging Techniques to Monitor Glucose Uptake, Cell Migration, and Vesicular Traffic: A Functional Study in Cancer Cells	-
Università degli Studi del Piemonte orientale "Amedeo Avogadro"	2020	Role of Diacylglycerol kinase alpha (DGKA) as a therapeutic target in Glioblastoma (GB)	-
Università degli Studi del Piemonte orientale "Amedeo Avogadro"	2019	Screening of the SHOX gene in a large cohort of short stature italian patients. Identification of novel likely pathogenic variants through functional characterization	-
Università degli Studi del Piemonte orientale "Amedeo Avogadro"	2014	Ecotoxicological profiles of metal engineered nanoparticles in mollusc bivalve Mytilus galloprovincialis	-
Università degli Studi del Piemonte orientale "Amedeo Avogadro"	2015	Search for genomic micro-rearrangements through array-CGH in patients with Intellectual Disability and Multiple Pituitary Hormone Deficiency, with standard and custom-design array platforms.	-
Università degli Studi del Piemonte orientale "Amedeo Avogadro"	2017	Unacylated ghrelin enhances satellite cell function and relieves the dystrophic phenotype in Duchenne muscular dystrophy mdx model	-
Università degli Studi del Piemonte orientale "Amedeo Avogadro"	2014	Hormonal aspects in paediatric obesity	-
Università degli Studi del Piemonte orientale "Amedeo Avogadro"	2015	Clinical impact of small TP53 mutated subclones in chronic lymphocytic leukemia	-
Università degli Studi del Piemonte orientale "Amedeo Avogadro"	2014	Molecular Determinants of Follicular Lymphoma Transformation to Diffuse Large B cell Lymphoma	-
Università degli Studi del Piemonte orientale "Amedeo Avogadro"	2017	Defining the causal association between human beta papillomavirus infection, keratinocyte stem cells expansion and skin cancer development	-
Università degli Studi del Piemonte orientale "Amedeo Avogadro"	2014	Role of munc13-4, sap and il-17 in the development of autoimmune lymphoproliferative syndrome	-

Prodotti della tipologia (ordinati per Data di deposito in Decrescente ordine): 301 a 320 di 686

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Prodotti recenti

Investigating the Impact of Microgravity on Cancer Cell Behavior and Drug Response: Implications for Novel Therapeutic Strategies

This PhD thesis investigates the profound impact of simulated microgravity (SMG) on both cancerous and non-cancerous cellular behavior and their drug responses. Specifically, this thesis examines cancer induction in pleura mesothelial cells and SMG-induced alterations in pancreatic ductal adenocarcinoma (PDAC) cells, highlighting Trichostatin A's (TSA) potential to restore normal cellular phenotypes. Ultimately, this work highlights simulated microgravity as an exciting new avenue for cancer ...

Clinical Roles for Biomarkers Of Sepsis - Associated Acute Kidney Injury

Sepsis is a life-threatening organ dysfunction caused by a dysregulated host response to infection. Acute kidney injury (AKI) is defined as an abrupt decrease of the glomerular filtration caused by different etiologies and is classified according to Kidney Disease: Improving Global Outcomes (KDIGO) criteria using serum creatinine (sCr) and urine output (UO). Acute kidney injury is one of the possible organ dysfunctions that could be present in sepsis (and also being one of its determinants). ...

The Role of the Mediterranean Diet in Addressing Obesity, Diabetes, and Cancer: a Global Perspective Across the Lifespan

There is a significant global change underway in the world, and urbanization, dietary changes, and the escalating burden of chronic disorders are reshaping the agendas for public health. Among these issues, overweight and obesity have emerged as significant global health issues, affecting billions of individuals and placing significant pressure on health systems. Overweight and obesity are not only clinical problems but also social, economic, and cultural ones with intricate multi-component s...

Optimizing Care Practice: Reducing Unplanned Hospitalizations among Nursing Home Residents

Introduzione: I residenti delle Residenze Sanitarie Assistenziali (RSA) rappresentano una popolazione vulnerabile, frequentemente soggetta a trasferimenti ospedalieri, talvolta potenzialmente evitabili. Tuttavia, la definizione di “evitabilità” è eterogenea e spesso non tiene conto della complessità clinica dei residenti o delle risorse. Obiettivo: Approfondire la comprensione e supportare lo sviluppo di strategie volte a ridurre le ospedalizzazioni potenzialmente evitabili tra gli anziani de...

Development, improvement, and application of new eco-sustainable friction materials: from laboratory development to the finished green product

The disc brake is an essential safety system in vehicles. The main component is the pad friction material, which consists of a mixture of 15-20 components bonded by an in-situ polymerised binder. Each component imparts specific properties that ensure adequate friction and wear performance under different braking conditions. According to their function, the components are classified into binders, reinforcements, abrasives, solid lubricants and functionalised fillers. The PhD project was carrie...

Development of biosensors based on cells for real - time environmental monitoring of estrogen and xenoestrogen dispersion and toxicity in water

The research focuses on the development of an innovative cell-based biosensor designed for real-time environmental monitoring of estrogenic and xenoestrogenic endocrine-disrupting chemicals (EEDCs) in water. Estrogens and related compounds, even at very low concentrations, pose serious ecological and health risks by interfering with hormonal signalling pathways. Existing analytical techniques, although sensitive and specific, are expensive, time-intensive, and unsuitable for on-site applicati...

Myeloid cell in FVIII immune response and their possible contribution in inhibitor formation

The major complication in Hemophilia A (HA) therapy is inhibitor formation against infused FVIII. While this is actively studied, the full mechanism remains unknown. Prior work from our lab suggests a role for plasmacytoid dendritic cells (pDCs) in inhibitor development. pDCs are traditionally known for type I interferon responses, but their antigen-presenting functions are under investigation. Another therapeutic option is Emicizumab, effective in HA patients with or without inhibitors, thou...

A New Sustainable Approach: Generation of a Serum-Free Cell Line for Enhanced Bioassay Applications

In vitro cell-based methods are essential for characterizing molecules and conducting potency bioassays for clinical and marketed drugs, as required by regulatory authorities. Fetal bovine serum (FBS) has been considered the gold standard for cell supplements, offering hormones, lipids, and growth factors that mimic the natural cellular environment. However, concerns about the variability and undefined nature of FBS compromise the reliability and consistency of scientific results. Additionall...

Being a migrant woman during disasters: a mixed-methods study exploring the impact of the COVID-19 pandemic in Milan, Italy

This PhD explored the experiences of migrant women (MW) in disasters through an intersectional lens, focusing on the COVID-19 pandemic in Milan, Italy. Using a transdisciplinary, mixed-methods approach, data collection included qualitative studies with MW and key informants, quantitative analyses of Sacco Hospital ED and EMERGENCY NGO datasets, and systematic literature reviews. The findings highlighted pre-existing vulnerabilities. The pandemic worsened their economic situation and marginal...

Agonists and Antagonists of the broadly tuned hTAS2R-receptors

TAS2R receptors (TAS2Rs) are responsible for detecting bitter taste and, with a few remarkable exceptions, are broadly tuned to recognize a diverse range of compounds. Their ectopic expression suggests additional roles beyond sensory perception, potentially offering health benefits. However, no universal bitter chemotype has yet emerged to guide the design of specific ligands, with most available data on TAS2Rs focusing on dietary phytochemicals. The presence of a lactone ring in structurally...

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