UNITesi

Università degli Studi del Piemonte orientale "Amedeo Avogadro": [686] Istituto

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Prodotti della tipologia (ordinati per Data di deposito in Decrescente ordine): 201 a 220 di 686
Istituto Anno di pubblicazione Titolo Autore file(s)
Università degli Studi del Piemonte orientale "Amedeo Avogadro" 2024 The identification of the PYRIN domain as mediator of IFI16-TLR4 interaction reveals a new class of endogenous inflammatory molecules -
Università degli Studi del Piemonte orientale "Amedeo Avogadro" 2025 GWAS era in multiple sclerosis: an integrative approach to explore genotype/phenotype interaction -
Università degli Studi del Piemonte orientale "Amedeo Avogadro" 2024 Microbiota of Vitis vinifera cv. Barbera grapes: a focus on the mycobiota and a look at the culturable indigenous Saccharomyces spp. strains under three different experimental conditions in vineyard -
Università degli Studi del Piemonte orientale "Amedeo Avogadro" 2024 Il Consiglio Superiore della Magistratura e i principi di autonomia e indipendenza : garanzia o minaccia? -
Università degli Studi del Piemonte orientale "Amedeo Avogadro" 2024 Spaces of the Diaspora: urban form and cultural practices of Russian immigrants in Europe and Asia in the first half of the twentieth century -
Università degli Studi del Piemonte orientale "Amedeo Avogadro" 2023 La prossenia in età ellenistica: i decreti ateniesi dalla guerra lamiaca alla conquista romana -
Università degli Studi del Piemonte orientale "Amedeo Avogadro" 2024 Divenire cani: la soggettività canina nella letteratura anglofona vittoriana e modernista -
Università degli Studi del Piemonte orientale "Amedeo Avogadro" 2024 Cell therapy for hemophilia A -
Università degli Studi del Piemonte orientale "Amedeo Avogadro" 2015 Beta human papillomavirus infection and skin cancer in immunocompromised host -
Università degli Studi del Piemonte orientale "Amedeo Avogadro" 2018 Targeted therapies in lung adenocarcinomas: new methodologies and new markers -
Università degli Studi del Piemonte orientale "Amedeo Avogadro" 2014 Expression and distinct functional roles of AKT isoforms in malignant pleural mesothelioma cells -
Università degli Studi del Piemonte orientale "Amedeo Avogadro" 2021 Sex differences in hepatitis C virus infection: characterisation of 17,β-estradiol-modulated antiviral defences in an HCV cell culture system -
Università degli Studi del Piemonte orientale "Amedeo Avogadro" 2016 Studio dei metaboliti del vino da vitigni coltivati in Piemonte attraverso l'uso della spettroscopia NMR -
Università degli Studi del Piemonte orientale "Amedeo Avogadro" 2021 Study of the growth, artemisinin production and leaf volatilome of some micropropagated Artemisia annua clones inoculated or not with beneficial soil microorganisms -
Università degli Studi del Piemonte orientale "Amedeo Avogadro" 2015 Development of novel approaches to modulate the immune response. Analysis of the effects of triggering the ICOS ligand and use of biocompatible/biodegradable nano/micro particles loaded with immunomodulatory molecules -
Università degli Studi del Piemonte orientale "Amedeo Avogadro" 2021 XPO1 mutations are a novel predictor of shorter time to first treatment in early stage CLL patients -
Università degli Studi del Piemonte orientale "Amedeo Avogadro" 2019 Resveratrol Attenuates the Malignant Phenotype of Ovarian Cancer Cells via Epigenetic Regulation of Autophagy -
Università degli Studi del Piemonte orientale "Amedeo Avogadro" 2021 Hybrid catalysts based on N-heterocyclic carbene anchored on hierarchical zeolites -
Università degli Studi del Piemonte orientale "Amedeo Avogadro" 2021 In vivo mouse models of virus-induced skin cancer, namely keratinocyte carcinoma and Merkel cell carcinoma -
Università degli Studi del Piemonte orientale "Amedeo Avogadro" 2016 Chemical and metabolic stability studies of propargylamine-containing drugs -
Prodotti della tipologia (ordinati per Data di deposito in Decrescente ordine): 201 a 220 di 686
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Prodotti recenti

Investigating the Impact of Microgravity on Cancer Cell Behavior and Drug Response: Implications for Novel Therapeutic Strategies

This PhD thesis investigates the profound impact of simulated microgravity (SMG) on both cancerous and non-cancerous cellular behavior and their drug responses. Specifically, this thesis examines cancer induction in pleura mesothelial cells and SMG-induced alterations in pancreatic ductal adenocarcinoma (PDAC) cells, highlighting Trichostatin A's (TSA) potential to restore normal cellular phenotypes. Ultimately, this work highlights simulated microgravity as an exciting new avenue for cancer ...

Clinical Roles for Biomarkers Of Sepsis - Associated Acute Kidney Injury

Sepsis is a life-threatening organ dysfunction caused by a dysregulated host response to infection. Acute kidney injury (AKI) is defined as an abrupt decrease of the glomerular filtration caused by different etiologies and is classified according to Kidney Disease: Improving Global Outcomes (KDIGO) criteria using serum creatinine (sCr) and urine output (UO). Acute kidney injury is one of the possible organ dysfunctions that could be present in sepsis (and also being one of its determinants). ...

The Role of the Mediterranean Diet in Addressing Obesity, Diabetes, and Cancer: a Global Perspective Across the Lifespan

There is a significant global change underway in the world, and urbanization, dietary changes, and the escalating burden of chronic disorders are reshaping the agendas for public health. Among these issues, overweight and obesity have emerged as significant global health issues, affecting billions of individuals and placing significant pressure on health systems. Overweight and obesity are not only clinical problems but also social, economic, and cultural ones with intricate multi-component s...

Optimizing Care Practice: Reducing Unplanned Hospitalizations among Nursing Home Residents

Introduzione: I residenti delle Residenze Sanitarie Assistenziali (RSA) rappresentano una popolazione vulnerabile, frequentemente soggetta a trasferimenti ospedalieri, talvolta potenzialmente evitabili. Tuttavia, la definizione di “evitabilità” è eterogenea e spesso non tiene conto della complessità clinica dei residenti o delle risorse. Obiettivo: Approfondire la comprensione e supportare lo sviluppo di strategie volte a ridurre le ospedalizzazioni potenzialmente evitabili tra gli anziani de...

Development, improvement, and application of new eco-sustainable friction materials: from laboratory development to the finished green product

The disc brake is an essential safety system in vehicles. The main component is the pad friction material, which consists of a mixture of 15-20 components bonded by an in-situ polymerised binder. Each component imparts specific properties that ensure adequate friction and wear performance under different braking conditions. According to their function, the components are classified into binders, reinforcements, abrasives, solid lubricants and functionalised fillers. The PhD project was carrie...

Development of biosensors based on cells for real - time environmental monitoring of estrogen and xenoestrogen dispersion and toxicity in water

The research focuses on the development of an innovative cell-based biosensor designed for real-time environmental monitoring of estrogenic and xenoestrogenic endocrine-disrupting chemicals (EEDCs) in water. Estrogens and related compounds, even at very low concentrations, pose serious ecological and health risks by interfering with hormonal signalling pathways. Existing analytical techniques, although sensitive and specific, are expensive, time-intensive, and unsuitable for on-site applicati...

Myeloid cell in FVIII immune response and their possible contribution in inhibitor formation

The major complication in Hemophilia A (HA) therapy is inhibitor formation against infused FVIII. While this is actively studied, the full mechanism remains unknown. Prior work from our lab suggests a role for plasmacytoid dendritic cells (pDCs) in inhibitor development. pDCs are traditionally known for type I interferon responses, but their antigen-presenting functions are under investigation. Another therapeutic option is Emicizumab, effective in HA patients with or without inhibitors, thou...

A New Sustainable Approach: Generation of a Serum-Free Cell Line for Enhanced Bioassay Applications

In vitro cell-based methods are essential for characterizing molecules and conducting potency bioassays for clinical and marketed drugs, as required by regulatory authorities. Fetal bovine serum (FBS) has been considered the gold standard for cell supplements, offering hormones, lipids, and growth factors that mimic the natural cellular environment. However, concerns about the variability and undefined nature of FBS compromise the reliability and consistency of scientific results. Additionall...

Being a migrant woman during disasters: a mixed-methods study exploring the impact of the COVID-19 pandemic in Milan, Italy

This PhD explored the experiences of migrant women (MW) in disasters through an intersectional lens, focusing on the COVID-19 pandemic in Milan, Italy. Using a transdisciplinary, mixed-methods approach, data collection included qualitative studies with MW and key informants, quantitative analyses of Sacco Hospital ED and EMERGENCY NGO datasets, and systematic literature reviews. The findings highlighted pre-existing vulnerabilities. The pandemic worsened their economic situation and marginal...

Agonists and Antagonists of the broadly tuned hTAS2R-receptors

TAS2R receptors (TAS2Rs) are responsible for detecting bitter taste and, with a few remarkable exceptions, are broadly tuned to recognize a diverse range of compounds. Their ectopic expression suggests additional roles beyond sensory perception, potentially offering health benefits. However, no universal bitter chemotype has yet emerged to guide the design of specific ligands, with most available data on TAS2Rs focusing on dietary phytochemicals. The presence of a lactone ring in structurally...

Scopri
Istituto
  • Università degli Studi del Piemon...681
Data di pubblicazione
  • 2020 - 2025266
  • 2010 - 2019270
  • 2000 - 2009142
  • 1997 - 19991
Settore disciplinare
  • Settore MED/04 - Patologia Generale52
  • Settore BIO/10 - Biochimica30
  • Settore BIO/14 - Farmacologia27
  • Settore CHIM/03 - Chimica General...22
  • Settore MED/15 - Malattie del Sangue22
  • Settore BIO/13 - Biologia Applicata17
  • Settore CHIM/08 - Chimica Farmace...16
  • Settore MED/07 - Microbiologia e ...16
  • Settore CHIM/06 - Chimica Organica15
  • Settore CHIM/01 - Chimica Analitica14
Accesso al fulltext
  • no fulltext463
  • open116
  • embargoed57
  • internalNetwork34
  • reserved6
  • mixed4
  • partially open1